PURPOSE: This is a meta-analysis of randomized and non-randomized studies comparing the clinical and radiological efficacy of minimally invasive (MI) and conventional open transforaminal lumbar interbody fusion (open-TLIF) for degenerative lumbar diseases. METHODS: A literature search of the MEDLINE database identified 11 studies that met our inclusion criteria. A total of 785 patients were examined. Pooled estimates of clinical and radiological outcomes, and corresponding 95% confidence intervals were calculated. RESULTS: The pooled data revealed that MI-TLIF was associated with less blood loss, shorter hospital stay, and a trend of better functional outcomes when compared with open-TLIF. However, MI-TLIF significantly increased the intraoperative X-ray exposure. Both techniques had similar operative time, complication rate, and re-operation rate. CONCLUSIONS: Based on the available evidence, MI-TLIF for degenerative lumbar diseases might lead to better patient-based outcomes. MI-TLIF would be a promising procedure, but extra efforts are needed to reduce its intraoperative radiation exposure. More randomized controlled trials are needed to compare these two surgical options.
PURPOSE: This is a meta-analysis of randomized and non-randomized studies comparing the clinical and radiological efficacy of minimally invasive (MI) and conventional open transforaminal lumbar interbody fusion (open-TLIF) for degenerative lumbar diseases. METHODS: A literature search of the MEDLINE database identified 11 studies that met our inclusion criteria. A total of 785 patients were examined. Pooled estimates of clinical and radiological outcomes, and corresponding 95% confidence intervals were calculated. RESULTS: The pooled data revealed that MI-TLIF was associated with less blood loss, shorter hospital stay, and a trend of better functional outcomes when compared with open-TLIF. However, MI-TLIF significantly increased the intraoperative X-ray exposure. Both techniques had similar operative time, complication rate, and re-operation rate. CONCLUSIONS: Based on the available evidence, MI-TLIF for degenerative lumbar diseases might lead to better patient-based outcomes. MI-TLIF would be a promising procedure, but extra efforts are needed to reduce its intraoperative radiation exposure. More randomized controlled trials are needed to compare these two surgical options.
Authors: Chan Wearn Benedict Peng; Wai Mun Yue; Seng Yew Poh; William Yeo; Seang Beng Tan Journal: Spine (Phila Pa 1976) Date: 2009-06-01 Impact factor: 3.468
Authors: S Reaungamornrat; T De Silva; A Uneri; J Goerres; M Jacobson; M Ketcha; S Vogt; G Kleinszig; A J Khanna; J-P Wolinsky; J L Prince; J H Siewerdsen Journal: Phys Med Biol Date: 2016-11-03 Impact factor: 3.609
Authors: Gursukhman S Sidhu; Erik Henkelman; Alexander R Vaccaro; Todd J Albert; Alan Hilibrand; D Greg Anderson; Jeffrey A Rihn Journal: Clin Orthop Relat Res Date: 2014-06 Impact factor: 4.176