OBJECTIVE: To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves (MRCL). METHODS: Antinociceptive activity was evaluated using acetic acid induced writhing test, formalin induced paw licking and tail immersion method in mice at doses of 100, 125 and 150 mg/kg bw. RESULTS: The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice. Preliminary phytochemical analysis suggested the presence of saponin, steroids and alkaloids. CONCLUSIONS: It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin, steroids and alkaloids in it.
OBJECTIVE: To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves (MRCL). METHODS: Antinociceptive activity was evaluated using acetic acid induced writhing test, formalin induced paw licking and tail immersion method in mice at doses of 100, 125 and 150 mg/kg bw. RESULTS: The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice. Preliminary phytochemical analysis suggested the presence of saponin, steroids and alkaloids. CONCLUSIONS: It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin, steroids and alkaloids in it.
Authors: Mohammad Hashem Hashempur; Fatemeh Khademi; Maryam Rahmanifard; Mohammad M Zarshenas Journal: J Evid Based Complementary Altern Med Date: 2017-01-24
Authors: Abu Montakim Tareq; Saifuddin Farhad; A B M Neshar Uddin; Muminul Hoque; Mst Samima Nasrin; Mir Md Rokib Uddin; Mohiminul Hasan; Arafat Sultana; Mst Shirajum Munira; Chadni Lyzu; S M Moazzem Hossen; A S M Ali Reza; Talha Bin Emran Journal: Heliyon Date: 2020-06-04
Authors: Niloy Barua; Md Arfin Ibn Aziz; Abu Montakim Tareq; Mohammed Aktar Sayeed; Najmul Alam; Nobi Ul Alam; Mohammad Amran Uddin; Chadni Lyzu; Talha Bin Emran Journal: Biochem Biophys Rep Date: 2020-06-09