AIM: To justify esophagectomy for elderly patients. PATIENTS AND METHODS: A total of 1,002 patients with thoracic esophageal cancer who underwent esophagectomy were divided into three groups: I (≤ 74 years old, n=898); II (75-79 years, n=81); and III (≥ 80 years, n=23). Historical changes were compared between the first surgical period (1964-1989) and the second period (1990-2011). RESULTS: The morbidity rates were 40%, 41% and 26% in the respective groups. Pulmonary complications decreased historically in groups II and III (36% to 15% and 43% to 0%, respectively). The mortality was higher in the older groups (4.8%, 8.6% and 13.0%, respectively); however, there was a marked historical decrease in groups II (18.2% to 5.1%) and III (28.6% to 6.3%). The 5-year survival improved from 5% to 35% in group II and from 0% to 17% in group III. CONCLUSION: The outcomes of esophagectomy for elderly patients have markedly improved, with acceptable mortality even in octogenarians.
AIM: To justify esophagectomy for elderly patients. PATIENTS AND METHODS: A total of 1,002 patients with thoracic esophageal cancer who underwent esophagectomy were divided into three groups: I (≤ 74 years old, n=898); II (75-79 years, n=81); and III (≥ 80 years, n=23). Historical changes were compared between the first surgical period (1964-1989) and the second period (1990-2011). RESULTS: The morbidity rates were 40%, 41% and 26% in the respective groups. Pulmonary complications decreased historically in groups II and III (36% to 15% and 43% to 0%, respectively). The mortality was higher in the older groups (4.8%, 8.6% and 13.0%, respectively); however, there was a marked historical decrease in groups II (18.2% to 5.1%) and III (28.6% to 6.3%). The 5-year survival improved from 5% to 35% in group II and from 0% to 17% in group III. CONCLUSION: The outcomes of esophagectomy for elderly patients have markedly improved, with acceptable mortality even in octogenarians.
Authors: Marcel Hochreiter; Maria Uhling; Leila Sisic; Thomas Bruckner; Alexandra Heininger; Andreas Hohn; Katja Ott; Thomas Schmidt; Marc Moritz Berger; Daniel Christoph Richter; Markus Büchler; Markus Alexander Weigand; Cornelius Johannes Busch Journal: Infection Date: 2018-06-05 Impact factor: 3.553
Authors: Renata Tabola; Katarzyna Augoff; Andrzej Lewandowski; Piotr Ziolkowski; Piotr Szelachowski; Krzysztof Grabowski Journal: Oncol Lett Date: 2016-07-18 Impact factor: 2.967
Authors: Aaron R Dezube; Lisa Cooper; Emanuele Mazzola; Daniel P Dolan; Daniel N Lee; Suden Kucukak; Luis E De Leon; Clark Dumontier; Bayonle Ademola; Emily Polhemus; Raphael Bueno; Abby White; Scott J Swanson; Michael T Jaklitsch; Laura Frain; Jon O Wee Journal: J Gastrointest Surg Date: 2022-03-31 Impact factor: 3.267