Literature DB >> 23564477

pH-controlled delivery of nanoparticles into tumor cells.

Liang Han1, Haojun Ma, Yubo Guo, Yuyang Kuang, Xi He, Chen Jiang.   

Abstract

Nanoparticles target tumor cells by pH-controlled means. Nanoparticles carry three synergistic delivery functions: 1) tumor tissue targeting by the EPR effect; 2) tumor cell targeting by pHLIP-mediated membrane-localization; and 3) tumor cell uptake by adsorptive-mediated endocytosis.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  gene delivery; nanoparticles; targeting acidity; tumor-targeting delivery

Mesh：

Substances：

Year:  2013        PMID： 23564477     DOI： 10.1002/adhm.201300013

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  14 in total

1.  Enhancement of radiation effect on cancer cells by gold-pHLIP.

Authors:  Michael P Antosh; Dayanjali D Wijesinghe; Samana Shrestha; Robert Lanou; Yun Hu Huang; Thomas Hasselbacher; David Fox; Nicola Neretti; Shouheng Sun; Natallia Katenka; Leon N Cooper; Oleg A Andreev; Yana K Reshetnyak
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-13       Impact factor: 11.205

2.  pH-sensitive pHLIP® coated niosomes.

Authors:  Mohan C Pereira; Monica Pianella; Da Wei; Anna Moshnikova; Carlotta Marianecci; Maria Carafa; Oleg A Andreev; Yana K Reshetnyak
Journal:  Mol Membr Biol       Date:  2017-08-09       Impact factor: 2.857

3.  Advanced targeted nanomedicine.

Authors:  Mohan C Pereira; Mohan C M Arachchige; Yana K Reshetnyak; Oleg A Andreev
Journal:  J Biotechnol       Date:  2015-01-20       Impact factor: 3.307

Review 4.  Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

Authors:  Yunlu Dai; Can Xu; Xiaolian Sun; Xiaoyuan Chen
Journal:  Chem Soc Rev       Date:  2017-05-18       Impact factor: 54.564

Review 5.  Applications of pHLIP Technology for Cancer Imaging and Therapy.

Authors:  Linden C Wyatt; Jason S Lewis; Oleg A Andreev; Yana K Reshetnyak; Donald M Engelman
Journal:  Trends Biotechnol       Date:  2017-04-21       Impact factor: 19.536

6.  The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions.

Authors:  Thomas T Tapmeier; Anna Moshnikova; John Beech; Danny Allen; Paul Kinchesh; Sean Smart; Adrian Harris; Alan McIntyre; Donald M Engelman; Oleg A Andreev; Yana K Reshetnyak; Ruth J Muschel
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-20       Impact factor: 11.205

Review 7.  Targeting diseased tissues by pHLIP insertion at low cell surface pH.

Authors:  Oleg A Andreev; Donald M Engelman; Yana K Reshetnyak
Journal:  Front Physiol       Date:  2014-03-13       Impact factor: 4.566

8.  Utilizing G2/M retention effect to enhance tumor accumulation of active targeting nanoparticles.

Authors:  Guanlian Hu; Xingli Cun; Shaobo Ruan; Kairong Shi; Yang Wang; Qifang Kuang; Chuan Hu; Wei Xiao; Qin He; Huile Gao
Journal:  Sci Rep       Date:  2016-06-08       Impact factor: 4.379

9.  Peptide mediated active targeting and intelligent particle size reduction-mediated enhanced penetrating of fabricated nanoparticles for triple-negative breast cancer treatment.

Authors:  Guanlian Hu; Xingli Chun; Yang Wang; Qin He; Huile Gao
Journal:  Oncotarget       Date:  2015-12-01

10.  Synthesis and characterization of pHLIP® coated gold nanoparticles.

Authors:  Jennifer L Daniels; Troy M Crawford; Oleg A Andreev; Yana K Reshetnyak
Journal:  Biochem Biophys Rep       Date:  2017-02-28
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