INTRODUCTION: Endometrial cancer survivors exhibit an increased incidence of subsequent neoplasms. PRESENTATION OF CASE: We present a patient with a history of endometrial cancer who, 3 years after surgery and radiotherapy, developed synchronous neoplasms of the breast, colon and rectum. The patient underwent abdominoperineal resection, a limited right colectomy, and excision of the breast tumour and axillary lymph node dissection. 18 months after surgery, there has been no disease recurrence. DISCUSSION: Multiple primary malignancies represent 16% of new cancer diagnoses. Research on subsequent malignancies after endometrial cancer has shown an increase in risk in colorectal, urinary bladder, lung and breast primaries. CONCLUSION: This case report illustrates the need for physicians to be aware of and counsel patients on the risk of subsequent cancers on endometrial cancer survivors.
INTRODUCTION:Endometrial cancer survivors exhibit an increased incidence of subsequent neoplasms. PRESENTATION OF CASE: We present a patient with a history of endometrial cancer who, 3 years after surgery and radiotherapy, developed synchronous neoplasms of the breast, colon and rectum. The patient underwent abdominoperineal resection, a limited right colectomy, and excision of the breast tumour and axillary lymph node dissection. 18 months after surgery, there has been no disease recurrence. DISCUSSION: Multiple primary malignancies represent 16% of new cancer diagnoses. Research on subsequent malignancies after endometrial cancer has shown an increase in risk in colorectal, urinary bladder, lung and breast primaries. CONCLUSION: This case report illustrates the need for physicians to be aware of and counsel patients on the risk of subsequent cancers on endometrial cancer survivors.
Authors: Lois B Travis; Charles S Rabkin; Linda Morris Brown; James M Allan; Blanche P Alter; Christine B Ambrosone; Colin B Begg; Neil Caporaso; Stephen Chanock; Angela DeMichele; William Douglas Figg; Mary K Gospodarowicz; Eric J Hall; Michie Hisada; Peter Inskip; Ruth Kleinerman; John B Little; David Malkin; Andrea K Ng; Kenneth Offit; Ching-Hon Pui; Leslie L Robison; Nathaniel Rothman; Peter G Shields; Louise Strong; Toshiyasu Taniguchi; Margaret A Tucker; Mark H Greene Journal: J Natl Cancer Inst Date: 2006-01-04 Impact factor: 13.506
Authors: Aaron P Brown; E Shannon Neeley; Theresa Werner; Andrew Patrick Soisson; Randall W Burt; David K Gaffney Journal: Int J Radiat Oncol Biol Phys Date: 2009-11-10 Impact factor: 7.038
Authors: Sanjeev Kumar; Jay P Shah; Christopher S Bryant; Awoniyi O Awonuga; Anthony N Imudia; Julie J Ruterbusch; Michele L Cote; Rouba Ali-Fehmi; Robert T Morris; John M Malone Journal: Gynecol Oncol Date: 2009-02-26 Impact factor: 5.482