Literature DB >> 2356244

In vitro activity of protoanemonin, an antifungal agent.

M L Martín1, L San Román, A Domínguez.   

Abstract

Protoanemonin, the lactone of gamma-hydroxy-vinylacrylic acid, isolated from Pulsatilla alpina has in vitro activity against fungi. The MIC is 15 micrograms/ml and RNA inhibition seems to be the first target of the drug. The LD50 of protoanemonin in male Swiss albino mice was 190 mg/kg.

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Year:  1990        PMID： 2356244     DOI： 10.1055/s-2006-960886

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  6 in total

1.  Too low to kill: concentration of the secondary metabolite ranunculin in buttercup pollen does not affect bee larval survival.

Authors:  Claudio Sedivy; Rafal Piskorski; Andreas Müller; Silvia Dorn
Journal:  J Chem Ecol       Date:  2012-06-19       Impact factor: 2.626

2.  In vitro activities of 3-(halogenated phenyl)-5-acyloxymethyl- 2,5-dihydrofuran-2-ones against common and emerging yeasts and molds.

Authors:  Vladimír Buchta; Milan Pour; Petra Kubanová; Luis Silva; Ivan Votruba; Marie Voprsálová; Radan Schiller; Helena Fáková; Marcel Spulák
Journal:  Antimicrob Agents Chemother       Date:  2004-03       Impact factor: 5.191

3.  Complete sequence analysis and antiviral screening of medicinal plants for human coxsackievirus a16 isolated in Korea.

Authors:  Jae-Hyoung Song; Kwisung Park; Aeri Shim; Bo-Eun Kwon; Jae-Hee Ahn; Young Jin Choi; Jae Kyung Kim; Sang-Gu Yeo; Kyungah Yoon; Hyun-Jeong Ko
Journal:  Osong Public Health Res Perspect       Date:  2015-01-09

4.  Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana.

Authors:  Wei Li; Xi Tao Yan; Ya Nan Sun; Thi Thanh Ngan; Sang Hee Shim; Young Ho Kim
Journal:  Biomol Ther (Seoul)       Date:  2014-07       Impact factor: 4.634

Review 5.  Therapeutic Potential of Ranunculus Species (Ranunculaceae): A Literature Review on Traditional Medicinal Herbs.

Authors:  Youn-Kyoung Goo
Journal:  Plants (Basel)       Date:  2022-06-17

6.  Genomic Resources of Three Pulsatilla Species Reveal Evolutionary Hotspots, Species-Specific Sites and Variable Plastid Structure in the Family Ranunculaceae.

Authors:  Monika Szczecińska; Jakub Sawicki
Journal:  Int J Mol Sci       Date:  2015-09-15       Impact factor: 5.923
  6 in total

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