Literature DB >> 23561442

Lin28: primal regulator of growth and metabolism in stem cells.

Ng Shyh-Chang1, George Q Daley.   

Abstract

In recent years, the highly conserved Lin28 RNA-binding proteins have emerged as factors that define stemness in several tissue lineages. Lin28 proteins repress let-7 microRNAs and influence mRNA translation, thereby regulating the self-renewal of mammalian embryonic stem cells. Subsequent discoveries revealed that Lin28a and Lin28b are also important in organismal growth and metabolism, tissue development, somatic reprogramming, and cancer. In this review, we discuss the Lin28 pathway and its regulation, outline its roles in stem cells, tissue development, and pathogenesis, and examine the ramifications for re-engineering mammalian physiology.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 23561442      PMCID： PMC3652335          DOI： 10.1016/j.stem.2013.03.005

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  153 in total

1.  Molecular basis for interaction of let-7 microRNAs with Lin28.

Authors:  Yunsun Nam; Casandra Chen; Richard I Gregory; James J Chou; Piotr Sliz
Journal:  Cell       Date:  2011-11-10       Impact factor: 41.582

2.  Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency.

Authors:  Anna Polesskaya; Sylvain Cuvellier; Irina Naguibneva; Arnaud Duquet; Eric G Moss; Annick Harel-Bellan
Journal:  Genes Dev       Date:  2007-05-01       Impact factor: 11.361

Review 3.  Healthy aging: is smaller better? - a mini-review.

Authors:  Andrzej Bartke
Journal:  Gerontology       Date:  2012-01-18       Impact factor: 5.140

4.  Extensive post-transcriptional regulation of microRNAs and its implications for cancer.

Authors:  J Michael Thomson; Martin Newman; Joel S Parker; Elizabeth M Morin-Kensicki; Tricia Wright; Scott M Hammond
Journal:  Genes Dev       Date:  2006-08-01       Impact factor: 11.361

5.  Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans.

Authors:  J E Sulston; H R Horvitz
Journal:  Dev Biol       Date:  1981-02       Impact factor: 3.582

6.  Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.

Authors:  Yosef Buganim; Dina A Faddah; Albert W Cheng; Elena Itskovich; Styliani Markoulaki; Kibibi Ganz; Sandy L Klemm; Alexander van Oudenaarden; Rudolf Jaenisch
Journal:  Cell       Date:  2012-09-14       Impact factor: 41.582

Review 7.  The let-7 family of microRNAs.

Authors:  Sarah Roush; Frank J Slack
Journal:  Trends Cell Biol       Date:  2008-09-04       Impact factor: 20.808

8.  Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1.

Authors:  Wei Wang; Jian Yang; Hui Liu; Dong Lu; Xiongfeng Chen; Zenon Zenonos; Lia S Campos; Roland Rad; Ge Guo; Shujun Zhang; Allan Bradley; Pentao Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-11       Impact factor: 11.205

9.  Lin28 promotes transformation and is associated with advanced human malignancies.

Authors:  Srinivas R Viswanathan; John T Powers; William Einhorn; Yujin Hoshida; Tony L Ng; Sara Toffanin; Maureen O'Sullivan; Jun Lu; Letha A Phillips; Victoria L Lockhart; Samar P Shah; Pradeep S Tanwar; Craig H Mermel; Rameen Beroukhim; Mohammad Azam; Jose Teixeira; Matthew Meyerson; Timothy P Hughes; Josep M Llovet; Jerald Radich; Charles G Mullighan; Todd R Golub; Poul H Sorensen; George Q Daley
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

10.  Efficient tumour formation by single human melanoma cells.

Authors:  Elsa Quintana; Mark Shackleton; Michael S Sabel; Douglas R Fullen; Timothy M Johnson; Sean J Morrison
Journal:  Nature       Date:  2008-12-04       Impact factor: 49.962
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  214 in total

1.  MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC.

Authors:  Maroof Alam; Rehan Ahmad; Hasan Rajabi; Donald Kufe
Journal:  Mol Cancer Res       Date:  2014-11-03       Impact factor: 5.852

2.  MicroRNA-125b-5p mediates post-transcriptional regulation of hepatitis B virus replication via the LIN28B/let-7 axis.

Authors:  Wanyu Deng; Xiaoyong Zhang; Zhiyong Ma; Yong Lin; Mengji Lu
Journal:  RNA Biol       Date:  2017-03-07       Impact factor: 4.652

Review 3.  Lin28 and let-7 in cell metabolism and cancer.

Authors:  Liem H Nguyen; Hao Zhu
Journal:  Transl Pediatr       Date:  2015-01

4.  Upregulating Lin28a Promotes Axon Regeneration in Adult Mice with Optic Nerve and Spinal Cord Injury.

Authors:  Fatima M Nathan; Yosuke Ohtake; Shuo Wang; Xinpei Jiang; Armin Sami; Hua Guo; Feng-Quan Zhou; Shuxin Li
Journal:  Mol Ther       Date:  2020-04-15       Impact factor: 11.454

Review 5.  Stem cell metabolism in tissue development and aging.

Authors:  Ng Shyh-Chang; George Q Daley; Lewis C Cantley
Journal:  Development       Date:  2013-06       Impact factor: 6.868

6.  Opposing Post-transcriptional Control of InR by FMRP and LIN-28 Adjusts Stem Cell-Based Tissue Growth.

Authors:  Arthur Luhur; Kasun Buddika; Ishara Surangi Ariyapala; Shengyao Chen; Nicholas Samuel Sokol
Journal:  Cell Rep       Date:  2017-12-05       Impact factor: 9.423

7.  The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7.

Authors:  Steven G Chaulk; Victoria J Lattanzi; Samantha E Hiemer; Richard P Fahlman; Xaralabos Varelas
Journal:  J Biol Chem       Date:  2013-12-09       Impact factor: 5.157

Review 8.  Mechanisms underlying the formation of induced pluripotent stem cells.

Authors:  Federico González; Danwei Huangfu
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2015-09-18       Impact factor: 5.814

9.  Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution.

Authors:  Ezinne Francess Mong; Kemal Marc Akat; John Canfield; John Lockhart; Jeffrey VanWye; Andrew Matar; John C M Tsibris; June K Wu; Thomas Tuschl; Hana Totary-Jain
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-05-03       Impact factor: 8.311

10.  Heterochronic regulation of lung development via the Lin28-Let-7 pathway.

Authors:  Nelly Komarovsky Gulman; Leah Armon; Tali Shalit; Achia Urbach
Journal:  FASEB J       Date:  2019-08-07       Impact factor: 5.191
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