Literature DB >> 23554203

Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.

Sepehr N Tabrizi1, Magnus Unemo, Daniel Golparian, Jimmy Twin, Athena E Limnios, Monica Lahra, Rebecca Guy.   

Abstract

GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.

Entities:  

Mesh：

Year:  2013        PMID： 23554203      PMCID： PMC3716077          DOI： 10.1128/JCM.00806-13

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  30 in total

1.  Clinical Neisseria gonorrhoeae isolate with a N. meningitidis porA gene and no prolyliminopeptidase activity, Sweden, 2011: danger of false-negative genetic and culture diagnostic results.

Authors:  D Golparian; E Johansson; M Unemo
Journal:  Euro Surveill       Date:  2012-03-01

Review 2.  Rapid tests for sexually transmitted infections (STIs): the way forward.

Authors:  R W Peeling; K K Holmes; D Mabey; A Ronald
Journal:  Sex Transm Infect       Date:  2006-12-06       Impact factor: 3.519

3.  A variant of Chlamydia trachomatis with deletion in cryptic plasmid: implications for use of PCR diagnostic tests.

Authors:  T Ripa; P Nilsson
Journal:  Euro Surveill       Date:  2006-11-09

4.  Screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections--2002.

Authors:  Robert E Johnson; Wilbert J Newhall; John R Papp; Joan S Knapp; Carolyn M Black; Thomas L Gift; Richard Steece; Lauri E Markowitz; Owen J Devine; Cathleen M Walsh; Susan Wang; Dorothy C Gunter; Kathleen L Irwin; Susan DeLisle; Stuart M Berman
Journal:  MMWR Recomm Rep       Date:  2002-10-18

5.  Performance of the GeneXpert CT/NG assay compared to that of the Aptima AC2 assay for detection of rectal Chlamydia trachomatis and Neisseria gonorrhoeae by use of residual Aptima Samples.

Authors:  S D Goldenberg; J Finn; E Sedudzi; J A White; C Y W Tong
Journal:  J Clin Microbiol       Date:  2012-09-19       Impact factor: 5.948

6.  Evaluation of the specificities of five DNA amplification methods for the detection of Neisseria gonorrhoeae.

Authors:  H M Palmer; H Mallinson; R L Wood; A J Herring
Journal:  J Clin Microbiol       Date:  2003-02       Impact factor: 5.948

7.  Neisseria gonorrhoeae false-positive result obtained from a pharyngeal swab by using the Roche cobas 4800 CT/NG assay in New Zealand in 2012.

Authors:  Arlo Upton; Collette Bromhead; David M Whiley
Journal:  J Clin Microbiol       Date:  2013-03-13       Impact factor: 5.948

8.  Validation of roche COBAS Amplicor assay for detection of Chlamydia trachomatis in rectal and pharyngeal specimens by an omp1 PCR assay.

Authors:  N A Lister; S N Tabrizi; C K Fairley; S Garland
Journal:  J Clin Microbiol       Date:  2004-01       Impact factor: 5.948

9.  Guidelines for the use and interpretation of nucleic acid detection tests for Neisseria gonorrhoeae in Australia: a position paper on behalf of the Public Health Laboratory Network.

Authors:  David W Smith; John W Tapsall; Gary Lum
Journal:  Commun Dis Intell Q Rep       Date:  2005

10.  Screening for Neisseria gonorrhoeae and Chlamydia trachomatis in men who have sex with men at male-only saunas.

Authors:  N A Lister; A Smith; S Tabrizi; P Hayes; N A Medland; S Garland; C K Fairley
Journal:  Sex Transm Dis       Date:  2003-12       Impact factor: 2.830
View more
  30 in total

1.  Review of use of a new rapid real-time PCR, the Cepheid GeneXpert® (Xpert) CT/NG assay, for Chlamydia trachomatis and Neisseria gonorrhoeae: results for patients while in a clinical setting.

Authors:  Charlotte A Gaydos
Journal:  Expert Rev Mol Diagn       Date:  2014-01-23       Impact factor: 5.225

2.  Inflammatory cytokine biomarkers to identify women with asymptomatic sexually transmitted infections and bacterial vaginosis who are at high risk of HIV infection.

Authors:  Lindi Masson; Kelly B Arnold; Francesca Little; Koleka Mlisana; David A Lewis; Nonhlanhla Mkhize; Hoyam Gamieldien; Sinaye Ngcapu; Leigh Johnson; Douglas A Lauffenburger; Quarraisha Abdool Karim; Salim S Abdool Karim; Jo-Ann S Passmore
Journal:  Sex Transm Infect       Date:  2015-10-28       Impact factor: 3.519

Review 3.  Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance.

Authors:  Namraj Goire; Monica M Lahra; Marcus Chen; Basil Donovan; Christopher K Fairley; Rebecca Guy; John Kaldor; David Regan; James Ward; Michael D Nissen; Theo P Sloots; David M Whiley
Journal:  Nat Rev Microbiol       Date:  2014-02-10       Impact factor: 60.633

4.  Point-by-Point Progress: Gonorrhea Point of Care Tests.

Authors:  Charlotte A Gaydos; Johan H Melendez
Journal:  Expert Rev Mol Diagn       Date:  2020-06-30       Impact factor: 5.225

Review 5.  New and developing diagnostic technologies for urinary tract infections.

Authors:  Michael Davenport; Kathleen E Mach; Linda M Dairiki Shortliffe; Niaz Banaei; Tza-Huei Wang; Joseph C Liao
Journal:  Nat Rev Urol       Date:  2017-03-01       Impact factor: 14.432

Review 6.  Point of care diagnostics for sexually transmitted infections: perspectives and advances.

Authors:  Charlotte Gaydos; Justin Hardick
Journal:  Expert Rev Anti Infect Ther       Date:  2014-02-03       Impact factor: 5.091

7.  Genomic Characterization of Emerging Bacterial Uropathogen Neisseria meningitidis, Which Was Misidentified as Neisseria gonorrhoeae by Nucleic Acid Amplification Testing.

Authors:  Kimberley V Sukhum; Sophonie Jean; Meghan Wallace; Neil Anderson; C A Burnham; Gautam Dantas
Journal:  J Clin Microbiol       Date:  2021-01-21       Impact factor: 5.948

Review 8.  The frontiers of addressing antibiotic resistance in Neisseria gonorrhoeae.

Authors:  Daniel H F Rubin; Jonathan D C Ross; Yonatan H Grad
Journal:  Transl Res       Date:  2020-02-29       Impact factor: 7.012

9.  Use of Nucleic Acid Amplification Testing for Diagnosis of Extragenital Sexually Transmitted Infections.

Authors:  Lisa A Cosentino; Claire S Danby; Lorna K Rabe; Ingrid Macio; Leslie A Meyn; Harold C Wiesenfeld; Sharon L Hillier
Journal:  J Clin Microbiol       Date:  2017-07-05       Impact factor: 5.948

10.  Field Evaluation of Xpert HPV Point-of-Care Test for Detection of Human Papillomavirus Infection by Use of Self-Collected Vaginal and Clinician-Collected Cervical Specimens.

Authors:  P Toliman; S G Badman; J Gabuzzi; S Silim; L Forereme; A Kumbia; B Kombuk; Z Kombati; J Allan; G Munnull; C Ryan; L M Vallely; A Kelly-Hanku; H Wand; G D L Mola; R Guy; P Siba; J M Kaldor; S N Tabrizi; A J Vallely
Journal:  J Clin Microbiol       Date:  2016-04-13       Impact factor: 5.948
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.