Literature DB >> 23486711

Neisseria gonorrhoeae false-positive result obtained from a pharyngeal swab by using the Roche cobas 4800 CT/NG assay in New Zealand in 2012.

Arlo Upton1, Collette Bromhead, David M Whiley.   

Abstract

The Roche cobas 4800 CT/NG assay is a commonly used commercial system for screening for Neisseria gonorrhoeae infection, and previous studies have shown the method to be highly sensitive and specific for urogenital samples. We present the first confirmed clinical N. gonorrhoeae false-positive result using the cobas 4800 NG assay, obtained from testing a pharyngeal swab sample and caused by cross-reaction with a commensal Neisseria strain.

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Year:  2013        PMID： 23486711      PMCID： PMC3647902          DOI： 10.1128/JCM.00485-13

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  11 in total

1.  Screening tests for Chlamydia trachomatis or Neisseria gonorrhoeae using the cobas 4800 PCR system do not require a second test to confirm: an audit of patients issued with equivocal results at a sexual health clinic in the Northwest of England, U.K.

Authors:  Mark J Hopkins; Godfrey Smith; Ian J Hart; Fath Alloba
Journal:  Sex Transm Infect       Date:  2012-06-01       Impact factor: 3.519

2.  Evaluation of six commercial nucleic acid amplification tests for detection of Neisseria gonorrhoeae and other Neisseria species.

Authors:  Sepehr N Tabrizi; Magnus Unemo; Athena E Limnios; Tiffany R Hogan; Stig-Ove Hjelmevoll; Susanne M Garland; John Tapsall
Journal:  J Clin Microbiol       Date:  2011-08-03       Impact factor: 5.948

3.  Is it time to move to nucleic acid amplification tests screening for pharyngeal and rectal gonorrhoea in men who have sex with men to improve gonorrhoea control?

Authors:  Christopher K Fairley; Marcus Y Chen; Catriona S Bradshaw; Sepehr N Tabrizi
Journal:  Sex Health       Date:  2011-03       Impact factor: 2.706

4.  Evaluation of the Roche cobas® CT/NG test for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in male urine.

Authors:  Stephanie N Taylor; Oliver Liesenfeld; Rebecca A Lillis; Barbara A Body; Melinda Nye; James Williams; Carol Eisenhut; Edward W Hook; Barbara Van Der Pol
Journal:  Sex Transm Dis       Date:  2012-07       Impact factor: 2.830

5.  Performance of the cobas CT/NG test compared to the Aptima AC2 and Viper CTQ/GCQ assays for detection of Chlamydia trachomatis and Neisseria gonorrhoeae.

Authors:  Barbara Van Der Pol; Oliver Liesenfeld; James A Williams; Stephanie N Taylor; Rebecca A Lillis; Barbara A Body; Mindy Nye; Carol Eisenhut; Edward W Hook
Journal:  J Clin Microbiol       Date:  2012-04-18       Impact factor: 5.948

6.  Evaluation of the cobas 4800 CT/NG test for detecting Chlamydia trachomatis and Neisseria gonorrhoeae.

Authors:  Rebecca Rockett; Namraj Goire; Athena Limnios; Mark Turra; Geoffrey Higgens; Stephen B Lambert; Cheryl Bletchly; Michael D Nissen; Theo P Sloots; David M Whiley
Journal:  Sex Transm Infect       Date:  2010-08-18       Impact factor: 3.519

7.  Introduction of routine polymerase chain reaction testing for Neisseria gonorrhoeae in a community laboratory.

Authors:  Arlo Upton; Janet Wilson; Liselle Bissessor
Journal:  Sex Health       Date:  2013-08       Impact factor: 2.706

8.  Identification of the uncultured bacillus of Whipple's disease.

Authors:  D A Relman; T M Schmidt; R P MacDermott; S Falkow
Journal:  N Engl J Med       Date:  1992-07-30       Impact factor: 91.245

Review 9.  Exploring 'best practice' for nucleic acid detection of Neisseria gonorrhoeae.

Authors:  David M Whiley; Suzanne M Garland; Geoffrey Harnett; Gary Lum; David W Smith; Sepehr N Tabrizi; Theo P Sloots; John W Tapsall
Journal:  Sex Health       Date:  2008-03       Impact factor: 2.706

10.  Guidelines for the use and interpretation of nucleic acid detection tests for Neisseria gonorrhoeae in Australia: a position paper on behalf of the Public Health Laboratory Network.

Authors:  David W Smith; John W Tapsall; Gary Lum
Journal:  Commun Dis Intell Q Rep       Date:  2005
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  4 in total

1.  Supplementary testing is not required in the cobas 4800 CT/NG test for Neisseria gonorrhoeae weak-positive urogenital samples.

Authors:  Collette Bromhead; Nadika Liyanarachchy; Julia Mayes; Arlo Upton; Michelle Balm
Journal:  J Clin Microbiol       Date:  2014-11-12       Impact factor: 5.948

2.  Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.

Authors:  Sepehr N Tabrizi; Magnus Unemo; Daniel Golparian; Jimmy Twin; Athena E Limnios; Monica Lahra; Rebecca Guy
Journal:  J Clin Microbiol       Date:  2013-04-03       Impact factor: 5.948

3.  High-Throughput Testing of Urogenital and Extragenital Specimens for Detection of Chlamydia Trachomatis and Neisseria Gonorrhoeae with Cobas® CT/NG.

Authors:  Elizabeth M Marlowe; David Hardy; Mark Krevolin; Peter Gohl; Alexander Bertram; Rodney Arcenas; Britta Seiverth; Tanja Schneider; Oliver Liesenfeld
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2017-09-11

Review 4.  The Laboratory Diagnosis of Neisseria gonorrhoeae: Current Testing and Future Demands.

Authors:  Thomas Meyer; Susanne Buder
Journal:  Pathogens       Date:  2020-01-31
  4 in total

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