Literature DB >> 23543822

Mechanical Properties and Tensile Failure Analysis of Novel Bio-absorbable Mg-Zn-Cu and Mg-Zn-Se Alloys for Endovascular Applications.

Dharam Persaud-Sharma1, Noah Budiansky, Anthony J McGoron.   

Abstract

In this paper, the mechanical properties and tensile failure mechanism of two novel bio-absorbable as-cast Mg-Zn-Se and Mg-Zn-Cu alloys for endovascular medical applications are characterized. Alloys were manufactured using an ARC melting process and tested as-cast with compositions of Mg-Zn-Se and Mg-Zn-Cu, being 98/1/1 wt.% respectively. Nanoindentation testing conducted at room temperature was used to characterize the elastic modulus (E) and surface hardness (H) for both the bare alloys and the air formed oxide layer. As compared to currently available shape memory alloys and degradable as-cast alloys, these experimental alloys possess superior as-cast mechanical properties that can increase their biocompatibility, degradation kinetics, and the potential for medical device creation.

Entities:  

Keywords:  Mg-Zn-Cu; Mg-Zn-Se; fracture analysis; magnesium alloys; mechanical properties

Year:  2012        PMID: 23543822      PMCID: PMC3611592          DOI: 10.3390/met3010023

Source DB:  PubMed          Journal:  Metals (Basel)        ISSN: 2075-4701            Impact factor:   2.351


  7 in total

1.  Biodegradable stents : "fulfilling the mission and stepping away".

Authors:  A Colombo; E Karvouni
Journal:  Circulation       Date:  2000-07-25       Impact factor: 29.690

2.  A novel approach to temporary stenting: degradable cardiovascular stents produced from corrodible metal-results 6-18 months after implantation into New Zealand white rabbits.

Authors:  M Peuster; P Wohlsein; M Brügmann; M Ehlerding; K Seidler; C Fink; H Brauer; A Fischer; G Hausdorf
Journal:  Heart       Date:  2001-11       Impact factor: 5.994

3.  Biodegradable Magnesium Alloys: A Review of Material Development and Applications.

Authors:  Dharam Persaud-Sharma; Anthony McGoron
Journal:  J Biomim Biomater Tissue Eng       Date:  2012-02-03

4.  New horizon of bioabsorbable stent.

Authors:  Shigeru Saito
Journal:  Catheter Cardiovasc Interv       Date:  2005-12       Impact factor: 2.692

Review 5.  The road to bioabsorbable stents: reaching clinical reality?

Authors:  Paul Erne; Matthias Schier; Therese J Resink
Journal:  Cardiovasc Intervent Radiol       Date:  2006 Jan-Feb       Impact factor: 2.740

6.  Electro and Magneto-Electropolished Surface Micro-Patterning on Binary and Ternary Nitinol.

Authors:  Dharam Persaud-Sharma; Norman Munroe; Anthony McGoron
Journal:  Trends Biomater Artif Organs       Date:  2012

Review 7.  Biodegradable metals for cardiovascular stent application: interests and new opportunities.

Authors:  Maryam Moravej; Diego Mantovani
Journal:  Int J Mol Sci       Date:  2011-06-29       Impact factor: 5.923

  7 in total
  2 in total

1.  Biocompatibility Assessment of Novel Bioresorbable Alloys Mg-Zn-Se and Mg-Zn-Cu for Endovascular Applications: In- Vitro Studies.

Authors:  Dharam Persaud-Sharma; Noah Budiansky; Anthony J McGoron
Journal:  J Biomim Biomater Tissue Eng       Date:  2013

2.  In Vitro Degradation Behavior of Ternary Mg-Zn-Se and Mg-Zn-Cu Alloys as Biomaterials.

Authors:  Dharam Persaud-Sharma; Noah Budiansky
Journal:  J Biomim Biomater Tissue Eng       Date:  2013
  2 in total

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