Literature DB >> 23539227

The relationship of age, race, and ethnicity with survival in dialysis patients.

Guofen Yan1, Keith C Norris, Alison J Yu, Jennie Z Ma, Tom Greene, Wei Yu, Alfred K Cheung.   

Abstract

BACKGROUND AND OBJECTIVES: Reports on the racial and ethnic differences in dialysis patient survival rates have been inconsistent. The literature suggests that these survival differences may be modified by age as well as categorizing white race as inclusive of Hispanic ethnicity. The goal of this study was to better understand these associations by examining survival among US dialysis patients by age, ethnicity, and race. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Between 1995 and 2009, 1,282,201 incident dialysis patients ages 18 years or older were identified in the United States Renal Data System. Dialysis survival was compared among non-Hispanic blacks, non-Hispanic whites, and Hispanics overall and stratified by seven age groups.
RESULTS: The median duration of follow-up was 22.3 months. Compared with non-Hispanic whites, a lower mortality risk was seen in Hispanics in all age groups. Consequently, when Hispanic patients were excluded from the white race, the mortality rates in white race all increased. Using non-Hispanic whites as the reference, a significantly lower mortality risk for non-Hispanic blacks was consistently observed in all age groups above 30 years (unadjusted hazard ratios ranged from 0.70 to 0.87; all P<0.001). In the 18- to 30-years age group, there remained an increased mortality risk in blacks versus non-Hispanic whites after adjustment for case mix (adjusted hazard ratio=1.19, 95% confidence interval=1.13-1.25).
CONCLUSIONS: The mortality risk was lowest in Hispanics, intermediate in non-Hispanic blacks, and highest in non-Hispanic whites. This pattern generally holds in all age groups except for the 18- to 30-years group, where the adjusted mortality rate for non-Hispanic blacks exceeds the adjusted mortality rate of non-Hispanic whites.

Entities:  

Mesh:

Year:  2013        PMID: 23539227      PMCID: PMC3675850          DOI: 10.2215/CJN.09180912

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN: 1555-9041            Impact factor:   8.237


  28 in total

1.  Race, age, and mortality among patients undergoing dialysis.

Authors:  Elani Streja; Miklos Z Molnar; Csaba P Kovesdy
Journal:  JAMA       Date:  2011-11-23       Impact factor: 56.272

2.  Impact of activated vitamin D and race on survival among hemodialysis patients.

Authors:  Myles Wolf; Joseph Betancourt; Yuchiao Chang; Anand Shah; Ming Teng; Hector Tamez; Orlando Gutierrez; Carlos A Camargo; Michal Melamed; Keith Norris; Meir J Stampfer; Neil R Powe; Ravi Thadhani
Journal:  J Am Soc Nephrol       Date:  2008-04-09       Impact factor: 10.121

3.  Racial differences in mortality among those with CKD.

Authors:  Rajnish Mehrotra; Dulcie Kermah; Linda Fried; Sharon Adler; Keith Norris
Journal:  J Am Soc Nephrol       Date:  2008-04-02       Impact factor: 10.121

4.  Hispanic ethnicity and vascular access use in patients initiating hemodialysis in the United States.

Authors:  Cristina M Arce; Aya A Mitani; Benjamin A Goldstein; Wolfgang C Winkelmayer
Journal:  Clin J Am Soc Nephrol       Date:  2011-11-23       Impact factor: 8.237

Review 5.  Survival disparities within American and Israeli dialysis populations: learning from similarities and distinctions across race and ethnicity.

Authors:  Kamyar Kalantar-Zadeh; Eliezer Golan; Tamy Shohat; Elani Streja; Keith C Norris; Joel D Kopple
Journal:  Semin Dial       Date:  2010 Nov-Dec       Impact factor: 3.455

6.  Contribution of major diseases to disparities in mortality.

Authors:  Mitchell D Wong; Martin F Shapiro; W John Boscardin; Susan L Ettner
Journal:  N Engl J Med       Date:  2002-11-14       Impact factor: 91.245

Review 7.  Racial and survival paradoxes in chronic kidney disease.

Authors:  Kamyar Kalantar-Zadeh; Csaba P Kovesdy; Stephen F Derose; Tamara B Horwich; Gregg C Fonarow
Journal:  Nat Clin Pract Nephrol       Date:  2007-09

Review 8.  Unraveling the racial disparities associated with kidney disease.

Authors:  Keith C Norris; Lawrence Y Agodoa
Journal:  Kidney Int       Date:  2005-09       Impact factor: 10.612

9.  Survival analysis of patients undergoing dialysis.

Authors:  P J Held; M V Pauly; L Diamond
Journal:  JAMA       Date:  1987-02-06       Impact factor: 56.272

10.  Dose of hemodialysis and survival: differences by race and sex.

Authors:  W F Owen; G M Chertow; J M Lazarus; E G Lowrie
Journal:  JAMA       Date:  1998-11-25       Impact factor: 56.272

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  48 in total

1.  Why minorities live longer on dialysis: an in-depth examination of the Danish nephrology registry.

Authors:  Connie M Rhee; Kamyar Kalantar-Zadeh; Keith C Norris
Journal:  Nephrol Dial Transplant       Date:  2016-01-06       Impact factor: 5.992

2.  Confounding of Race/Ethnicity and Age in the Survival among Veterans Obtaining Dialysis in VA and Non-VA Settings.

Authors:  Guofen Yan
Journal:  J Am Soc Nephrol       Date:  2019-05-16       Impact factor: 10.121

3.  Lesson Learned in Mortality and Kidney Transplant Outcomes among Pediatric Dialysis Patients.

Authors:  Marciana Laster; Keith C Norris
Journal:  J Am Soc Nephrol       Date:  2017-03-07       Impact factor: 10.121

Review 4.  Hemodialysis Disparities in African Americans: The Deeply Integrated Concept of Race in the Social Fabric of Our Society.

Authors:  Keith C Norris; Sandra F Williams; Connie M Rhee; Susanne B Nicholas; Csaba P Kovesdy; Kamyar Kalantar-Zadeh; L Ebony Boulware
Journal:  Semin Dial       Date:  2017-03-09       Impact factor: 3.455

5.  Differences in access to kidney transplantation between Hispanic and non-Hispanic whites by geographic location in the United States.

Authors:  Cristina M Arce; Benjamin A Goldstein; Aya A Mitani; Colin R Lenihan; Wolfgang C Winkelmayer
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-10       Impact factor: 8.237

6.  Regional Variations in the Interpretation of the End-Stage Renal Disease Thirty-Month Coordination Period: Potential Implications for Patient Care.

Authors:  Rubette Harford; Mary Jo Clark; Guofen Yan; Jose Flaque; Jose Colon; Francisco Torre; Ylene Rodriguez; Keith C Norris
Journal:  J Health Care Poor Underserved       Date:  2017

7.  Survival on dialysis among American Indians and Alaska Natives with diabetes in the United States, 1995-2010.

Authors:  Nilka Ríos Burrows; Pyone Cho; Kai McKeever Bullard; Andrew S Narva; Paul W Eggers
Journal:  Am J Public Health       Date:  2014-04-22       Impact factor: 9.308

8.  Impact of age, race and ethnicity on dialysis patient survival and kidney transplantation disparities.

Authors:  Connie M Rhee; Paungpaga Lertdumrongluk; Elani Streja; Jongha Park; Hamid Moradi; Wei Ling Lau; Keith C Norris; Allen R Nissenson; Alpesh N Amin; Csaba P Kovesdy; Kamyar Kalantar-Zadeh
Journal:  Am J Nephrol       Date:  2014-02-15       Impact factor: 3.754

9.  Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis.

Authors:  Julia J Scialla; Rulan S Parekh; Joseph A Eustace; Brad C Astor; Laura Plantinga; Bernard G Jaar; Tariq Shafi; Josef Coresh; Neil R Powe; Michal L Melamed
Journal:  Am J Nephrol       Date:  2015-08-20       Impact factor: 3.754

10.  Age, Race and Cardiovascular Outcomes in African American Veterans.

Authors:  Keith C Norris; George A Mensah; L Ebony Boulware; Jun L Lu; Jennie Z Ma; Elani Streja; Miklos Z Molnar; Kamyar Kalantar-Zadeh; Csaba P Kovesdy
Journal:  Ethn Dis       Date:  2016-07-21       Impact factor: 1.847

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