Literature DB >> 23535806

A meta-analysis of functional outcome among older adults with traumatic brain injury.

Amanda McIntyre1, Swati Mehta, Shannon Janzen, JoAnne Aubut, Robert W Teasell.   

Abstract

OBJECTIVE: The objective of this study was to determine rates of functional outcomes, based on Glasgow Outcome Scale scores, among older adults (>60 years) after a traumatic brain injury.
METHODS: An extensive database search was conducted. To be included all articles were published in English, included individuals 60 years or older, explicitly stated in-hospital GCS scores and GOS scores within one year post-TBI. Data was pooled on patient characteristics, mortality rates, time to death, and study design.
RESULTS: A total of 11 studies were included in this review. Among individuals with severe TBI, favourable, unfavourable, and fatal outcomes were observed in 7.9% (CI 5.3%-11.8%), 13.8% (CI 10.0%-18.8%) and 79.3% (CI 73.2%-84.4%), respectively. Among those with moderate TBI, favourable, unfavourable, and fatal outcomes were observed in 32.2% (CI 18.0%-50.7%), 29.5% (CI 16.5%-47.0%), and 42.5% (CI 26.1%-60.7%), respectively. Among those with mild TBI, favourable, unfavourable, and fatal outcomes were observed in 80.5% (CI 53.2%-93.7%), 7.0% (CI 1.9%-22.7%), and 10.7% (CI 3.1%-30.9%), respectively.
CONCLUSION: This study has demonstrated the significant interaction between GCS and GOS among older adults. Although older adults may require aggressive and comprehensive treatment to achieve these favourable outcomes, high rates of unfavourable outcome should not justify the use of conservative treatment.

Entities:  

Mesh:

Year:  2013        PMID: 23535806     DOI: 10.3233/NRE-130862

Source DB:  PubMed          Journal:  NeuroRehabilitation        ISSN: 1053-8135            Impact factor:   2.138


  13 in total

1.  The impact of inpatient palliative care on end-of-life care among older trauma patients who die after hospital discharge.

Authors:  Elizabeth J Lilley; Katherine C Lee; John W Scott; Nicole J Krumrei; Adil H Haider; Ali Salim; Rajan Gupta; Zara Cooper
Journal:  J Trauma Acute Care Surg       Date:  2018-11       Impact factor: 3.313

2.  Defining Serious Illness Among Adult Surgical Patients.

Authors:  Katherine C Lee; Anne M Walling; Steven S Senglaub; Amy S Kelley; Zara Cooper
Journal:  J Pain Symptom Manage       Date:  2019-08-09       Impact factor: 3.612

3.  Predictors of ICU admission and patient outcome for traumatic brain injury in a Tanzanian referral hospital: Implications for improving treatment guidelines.

Authors:  Brandon A Knettel; Christine T Knettel; Francis Sakita; Justin G Myers; Theresia Edward; Linda Minja; Blandina T Mmbaga; João Ricardo Nickenig Vissoci; Catherine Staton
Journal:  Injury       Date:  2022-03-25       Impact factor: 2.687

Review 4.  Integrated Health Care Management of Moderate to Severe TBI in Older Patients-A Narrative Review.

Authors:  Rahel Schumacher; René M Müri; Bernhard Walder
Journal:  Curr Neurol Neurosci Rep       Date:  2017-10-07       Impact factor: 5.081

5.  Functional motor improvement during inpatient rehabilitation among older adults with traumatic brain injury.

Authors:  Emily Evans; Cicely Krebill; Roee Gutman; Linda Resnik; Mark R Zonfrillo; Stephanie N Lueckel; Wenhan Zhang; Raj G Kumar; Kristen Dams-O'Connor; Kali S Thomas
Journal:  PM R       Date:  2021-06-28       Impact factor: 2.218

6.  Successful Community Discharge Among Older Adults With Traumatic Brain Injury in Skilled Nursing Facilities.

Authors:  Emily Evans; Roee Gutman; Linda Resnik; Mark R Zonfrillo; Stephanie N Lueckel; Raj G Kumar; Frank DeVone; Kristen Dams-O'Connor; Kali S Thomas
Journal:  J Head Trauma Rehabil       Date:  2021 May-Jun 01       Impact factor: 3.117

7.  Understanding Traumatic Brain Injury in Females: A State-of-the-Art Summary and Future Directions.

Authors:  Eve M Valera; Annie-Lori C Joseph; Katherine Snedaker; Matthew J Breiding; Courtney L Robertson; Angela Colantonio; Harvey Levin; Mary Jo Pugh; Deborah Yurgelun-Todd; Rebekah Mannix; Jeffrey J Bazarian; L Christine Turtzo; Lyn S Turkstra; Lisa Begg; Diana M Cummings; Patrick S F Bellgowan
Journal:  J Head Trauma Rehabil       Date:  2021-01-01       Impact factor: 3.117

8.  Mortality and One-Year Functional Outcome in Elderly and Very Old Patients with Severe Traumatic Brain Injuries: Observed and Predicted.

Authors:  Cecilie Røe; Toril Skandsen; Unn Manskow; Tiina Ader; Audny Anke
Journal:  Behav Neurol       Date:  2015-11-24       Impact factor: 3.342

9.  Repetitive Traumatic Brain Injury Among Older Adults.

Authors:  Aparna Vadlamani Chauhan; Jack Guralnik; Susan dosReis; John D Sorkin; Neeraj Badjatia; Jennifer S Albrecht
Journal:  J Head Trauma Rehabil       Date:  2021-07-26       Impact factor: 3.117

10.  Older Age Results in Differential Gene Expression after Mild Traumatic Brain Injury and Is Linked to Imaging Differences at Acute Follow-up.

Authors:  Young-Eun Cho; Lawrence L Latour; Hyungsuk Kim; L Christine Turtzo; Anlys Olivera; Whitney S Livingston; Dan Wang; Christiana Martin; Chen Lai; Ann Cashion; Jessica Gill
Journal:  Front Aging Neurosci       Date:  2016-07-13       Impact factor: 5.750

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