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Literature DB >> 23531995

Controlling the rate of coiled coil driven membrane fusion.

Tingting Zheng¹, Jens Voskuhl, Frank Versluis, Harshal R Zope, Itsuro Tomatsu, Hana Robson Marsden, Alexander Kros.

Abstract

Sets of complementary lipidated coiled-coil forming peptides that fuse membrane fusion have been designed. The influence of the coiled-coil motif on the rate of liposome fusion was studied, by varying the number of heptad repeats. We found that an increased coiled-coil stability of complementary peptides translates into increased rates of membrane fusion of liposomes.

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Year: 2013 PMID： 23531995 DOI： 10.1039/c3cc38926j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

15 in total

1. Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels.

Authors: Néstor López Mora; Jesper S Hansen; Yue Gao; Andrew A Ronald; Roxanne Kieltyka; Noah Malmstadt; Alexander Kros
Journal: Chem Commun (Camb) Date: 2014-02-25 Impact factor: 6.222

2. Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring.

Authors: Swapnil Wagle; Vasil N Georgiev; Tom Robinson; Rumiana Dimova; Reinhard Lipowsky; Andrea Grafmüller
Journal: Sci Rep Date: 2019-05-22 Impact factor: 4.379

3. Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion.

Authors: Filip Savić; Torben-Tobias Kliesch; Sarah Verbeek; Chunxiao Bao; Jan Thiart; Alexander Kros; Burkhard Geil; Andreas Janshoff
Journal: Biophys J Date: 2016-05-24 Impact factor: 4.033

4. A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion.

Authors: Martin Rabe; Christopher Aisenbrey; Kristyna Pluhackova; Vincent de Wert; Aimee L Boyle; Didjay F Bruggeman; Sonja A Kirsch; Rainer A Böckmann; Alexander Kros; Jan Raap; Burkhard Bechinger
Journal: Biophys J Date: 2016-11-15 Impact factor: 4.033

5. All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics.

Authors: Sun Young Woo; Hwankyu Lee
Journal: Sci Rep Date: 2016-03-01 Impact factor: 4.379

Controlling the rate of coiled coil driven membrane fusion.

1. Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels.

2. Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring.

3. Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion.

4. A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion.

5. All-atom simulations and free-energy calculations of coiled-coil peptides with lipid bilayers: binding strength, structural transition, and effect on lipid dynamics.

6. Resolving single membrane fusion events on planar pore-spanning membranes.

7. Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes.

8. Peptide-Mediated Liposome Fusion: The Effect of Anchor Positioning.

9. Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion.

Review 10. Molecular Simulations of PEGylated Biomolecules, Liposomes, and Nanoparticles for Drug Delivery Applications.