Literature DB >> 2353064

tert-Butyl hydroperoxide-induced injury in isolated rat hepatocytes: a model for studying anti-hepatotoxic crude drugs.

M Joyeux1, A Rolland, J Fleurentin, F Mortier, P Dorfman.   

Abstract

Tert-butyl hydroperoxide induces in freshly isolated rat hepatocytes malonaldehyde formation and lacticodehydrogenase and aspartate amino-transferase leakage. This model, when adapted to crude extracts, permits the demonstration of both anti-lipoperoxidant and antihepatotoxic activity of reference products like quercetin and silymarin and plant extracts like Rosmarinus officinalis and Eschscholzia californica.

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Year:  1990        PMID： 2353064     DOI： 10.1055/s-2006-960918

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  11 in total

1.  Cardiotoxicity studies using freshly isolated calcium-tolerant cardiomyocytes from adult rat.

Authors:  F Remião; H Carmo; F Carvalho; M L Bastos
Journal:  In Vitro Cell Dev Biol Anim       Date:  2001-01       Impact factor: 2.416

2.  Prevention of radiation induced hematological alterations by medicinal plant Rosmarinus officinalis, in mice.

Authors:  Garima Sancheti; P K Goyal
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-11-13

3.  Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes--comparison with silybin.

Authors:  E R Fernandes; F D Carvalho; F G Remião; M L Bastos; M M Pinto; O R Gottlieb
Journal:  Pharm Res       Date:  1995-11       Impact factor: 4.200

4.  Effect of antioxidant supplementation on the total yield, oxidative stress levels, and multipotency of bone marrow-derived human mesenchymal stromal cells.

Authors:  Hugo Alves; Anouk Mentink; Bach Le; Clemens A van Blitterswijk; Jan de Boer
Journal:  Tissue Eng Part A       Date:  2013-01-05       Impact factor: 3.845

5.  Hepatoprotective activity of the Phyllanthus species on tert-butyl hydroperoxide (t-BH)-induced cytotoxicity in HepG2 cells.

Authors:  Surendra Kumar Sharma; Sheela Meruga Arogya; Deepak Hiraganahalli Bhaskarmurthy; Amit Agarwal; Chandrasekaran Chinampudar Velusami
Journal:  Pharmacogn Mag       Date:  2011-07       Impact factor: 1.085

6.  Effects of supplemental levels of bazhen on growth performances, serum traits, immunity, meat quality and antioxidant activity of taiwan country chickens.

Authors:  Tu-Fa Lien; Kou-Joong Lin; Ling-Ling Yang; Lih-Geeng Chen
Journal:  Asian-Australas J Anim Sci       Date:  2013-05       Impact factor: 2.509

Review 7.  Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An Overview.

Authors:  Divya Singh; William C Cho; Ghanshyam Upadhyay
Journal:  Front Physiol       Date:  2016-01-26       Impact factor: 4.566

Review 8.  Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities.

Authors:  Nooshin Mohammadzadeh; Soghra Mehri; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2017-05       Impact factor: 2.699

Review 9.  Some in vitro/in vivo chemically-induced experimental models of liver oxidative stress in rats.

Authors:  Rumyana Simeonova; Magdalena Kondeva-Burdina; Vessela Vitcheva; Mitka Mitcheva
Journal:  Biomed Res Int       Date:  2014-01-16       Impact factor: 3.411

10.  Antioxidant Effects of Lycopene and Ubiquinol-10 on the Oxidative Stress in Rat Hepatocytes Induced by Tert-Buthyl Hydroperoxide.

Authors:  Mohammad-Reza Safari
Journal:  EJIFCC       Date:  2010-03-25
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