| Literature DB >> 23524684 |
Sofia Edin1, Maria L Wikberg, Per-Arne Oldenborg, Richard Palmqvist.
Abstract
Macrophages play a complex role in tumor progression since they can exert both tumor-preventing (M1 macrophages) and tumor-promoting (M2 macrophages) activities. In colorectal carcinoma (CRC), at odds to many other cancers, macrophage infiltration has been correlated with an improved patient survival. In a recent study, we have evaluated the distribution of M1 and M2 macrophage subtypes in CRC and their impact on patient prognosis.Entities:
Keywords: CpG island methylator phenotype; colorectal cancer; macrophage subtypes; microsatellite instability; prognosis
Year: 2013 PMID: 23524684 PMCID: PMC3601174 DOI: 10.4161/onci.23038
Source DB: PubMed Journal: Oncoimmunology ISSN: 2162-4011 Impact factor: 8.110