Literature DB >> 23519781

Notch signaling and bone remodeling.

Jenna Regan1, Fanxin Long.   

Abstract

Notch signaling plays context-dependent roles in the development and maintenance of many cell types and tissues in mammals. In the skeleton, both osteoblasts and osteoclasts require Notch signaling for proper differentiation and function, and the specific roles of Notch are dependent on the differentiation status of the cell. The recent discovery of activating NOTCH2 mutations as the cause of Hajdu-Cheney syndrome has highlighted the significance of Notch signaling in human bone physiology.

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Year:  2013        PMID： 23519781      PMCID： PMC3645324          DOI： 10.1007/s11914-013-0145-4

Source DB:  PubMed          Journal:  Curr Osteoporos Rep        ISSN： 1544-1873            Impact factor:   5.096


  41 in total

1.  Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.

Authors:  Andrew P Weng; Adolfo A Ferrando; Woojoong Lee; John P Morris; Lewis B Silverman; Cheryll Sanchez-Irizarry; Stephen C Blacklow; A Thomas Look; Jon C Aster
Journal:  Science       Date:  2004-10-08       Impact factor: 47.728

2.  Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells.

Authors:  Takayuki Yamada; Hidetoshi Yamazaki; Toshiyuki Yamane; Miya Yoshino; Hiromi Okuyama; Motokazu Tsuneto; Tomomi Kurino; Shin-Ichi Hayashi; Seiji Sakano
Journal:  Blood       Date:  2002-10-31       Impact factor: 22.113

3.  Osteoblast lineage-specific effects of notch activation in the skeleton.

Authors:  Ernesto Canalis; Kristen Parker; Jian Q Feng; Stefano Zanotti
Journal:  Endocrinology       Date:  2012-12-28       Impact factor: 4.736

4.  Vertebral anomalies in children with Alagille syndrome: an analysis of 50 consecutive patients.

Authors:  Evelyn Sanderson; Vanessa Newman; Susan F Haigh; Alastair Baker; Paul S Sidhu
Journal:  Pediatr Radiol       Date:  2001-12-15

5.  Syndrome of Alagille: radiological and sonographic findings. A review of 37 cases.

Authors:  T Berrocal; E Gamo; J Navalón; C Prieto; I Al-Assir; P Cortés; I Pastor; L Hierro
Journal:  Eur Radiol       Date:  1997       Impact factor: 5.315

Review 6.  Hajdu--Cheney syndrome: evolution of phenotype and clinical problems.

Authors:  A M Brennan; R M Pauli
Journal:  Am J Med Genet       Date:  2001-05-15

7.  Notch signaling controls multiple steps of pancreatic differentiation.

Authors:  L Charles Murtaugh; Ben Z Stanger; Kristen M Kwan; Douglas A Melton
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-01       Impact factor: 11.205

8.  Notch 1 impairs osteoblastic cell differentiation.

Authors:  Maria Sciaudone; Elisabetta Gazzerro; Leah Priest; Anne M Delany; Ernesto Canalis
Journal:  Endocrinology       Date:  2003-09-04       Impact factor: 4.736

9.  Outcome of syndromic paucity of interlobular bile ducts (Alagille syndrome) with onset of cholestasis in infancy.

Authors:  E J Hoffenberg; M R Narkewicz; J M Sondheimer; D J Smith; A Silverman; R J Sokol
Journal:  J Pediatr       Date:  1995-08       Impact factor: 4.406

10.  Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.

Authors:  Sally L Dunwoodie; Melanie Clements; Duncan B Sparrow; Xin Sa; Ronald A Conlon; Rosa S P Beddington
Journal:  Development       Date:  2002-04       Impact factor: 6.868
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  30 in total

1.  Notch signaling inhibition protects against LPS mediated osteolysis.

Authors:  Peeyush N Goel; Alexander J Egol; Yasaman Moharrer; Beatrix Brandfield-Harvey; Jaimo Ahn; Jason W Ashley
Journal:  Biochem Biophys Res Commun       Date:  2019-06-05       Impact factor: 3.575

Review 2.  Notch Signaling in Osteogenesis, Osteoclastogenesis, and Angiogenesis.

Authors:  Zhengliang Luo; Xifu Shang; Hao Zhang; Guangxi Wang; Patrick A Massey; Shane R Barton; Christopher G Kevil; Yufeng Dong
Journal:  Am J Pathol       Date:  2019-08       Impact factor: 4.307

Review 3.  TNF and Bone Remodeling.

Authors:  Baohong Zhao
Journal:  Curr Osteoporos Rep       Date:  2017-06       Impact factor: 5.096

Review 4.  Therapeutic modulation of Notch signalling--are we there yet?

Authors:  Emma R Andersson; Urban Lendahl
Journal:  Nat Rev Drug Discov       Date:  2014-05       Impact factor: 84.694

5.  The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.

Authors:  Rialnat A Lawal; Xichao Zhou; Kaylind Batey; Corey M Hoffman; Mary A Georger; Freddy Radtke; Matthew J Hilton; Lianping Xing; Benjamin J Frisch; Laura M Calvi
Journal:  J Bone Miner Res       Date:  2017-03-09       Impact factor: 6.741

6.  Bone Structural Characteristics and Response to Bisphosphonate Treatment in Children With Hajdu-Cheney Syndrome.

Authors:  Sophia Sakka; Rachel I Gafni; Justin H Davies; Bart Clarke; Peter Tebben; Mark Samuels; Vrinda Saraff; Klaus Klaushofer; Nadja Fratzl-Zelman; Paul Roschger; Frank Rauch; Wolfgang Högler
Journal:  J Clin Endocrinol Metab       Date:  2017-11-01       Impact factor: 5.958

7.  Downregulation of Notch modulators, tetraspanin 5 and 10, inhibits osteoclastogenesis in vitro.

Authors:  Jian Zhou; Toshifumi Fujiwara; Shiqiao Ye; Xiaolin Li; Haibo Zhao
Journal:  Calcif Tissue Int       Date:  2014-06-17       Impact factor: 4.333

Review 8.  The role and clinical implications of the endosteal niche and osteoblasts in regulating leukemia.

Authors:  S Azizidoost; V Vijay; C R Cogle; E Khodadi; N Saki
Journal:  Clin Transl Oncol       Date:  2017-03-09       Impact factor: 3.405

9.  Anabolic actions of Notch on mature bone.

Authors:  Peng Liu; Yilin Ping; Meng Ma; Demao Zhang; Connie Liu; Samir Zaidi; Song Gao; Yaoting Ji; Feng Lou; Fanyuan Yu; Ping Lu; Agnes Stachnik; Mingru Bai; Chengguo Wei; Liaoran Zhang; Ke Wang; Rong Chen; Maria I New; David W Rowe; Tony Yuen; Li Sun; Mone Zaidi
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-28       Impact factor: 11.205

10.  Bone geometry and microarchitecture deficits in children with Alagille syndrome.

Authors:  Joseph M Kindler; Ellen L Mitchell; David A Piccoli; Adda Grimberg; Mary B Leonard; Kathleen M Loomes; Babette S Zemel
Journal:  Bone       Date:  2020-08-11       Impact factor: 4.398
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