Literature DB >> 23519554

Nucleophilic addition to 2,3-pyridyne and synthesis of benzonaphthyridinones.

Yuesi Fang1, Richard C Larock.   

Abstract

A study of the nucleophilic addition of amines to 2,3-pyridyne has been carried out. 2-Aminopyridines have been generated exclusively. A series of benzonaphthyridinones have been synthesized by reacting 2,3-pyridyne and o-aminobenzoates.

Entities:  

Keywords:  2,3-Pyridyne; Amination; Annulation; Benzonaphthyridinone; Heterocycle

Year:  2012        PMID： 23519554      PMCID： PMC3600655          DOI： 10.1016/j.tet.2012.02.002

Source DB:  PubMed          Journal:  Tetrahedron        ISSN： 0040-4020            Impact factor:   2.457


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