Literature DB >> 23513044

Towards identifying a characteristic neuropsychological profile for fetal alcohol spectrum disorders. 1. Analysis of the Motherisk FASD clinic.

Kelly Nash1, Sara Stevens, Joanne Rovet, Ellen Fantus, Irena Nulman, Donna Sorbara, Gideon Koren.   

Abstract

OBJECTIVE: Children with FASD display a heterogeneous profile and may have deficits in physical, behavioural, emotional, and social functioning, as the result of prenatal alcohol exposure. The major objective of the current study was to identify if a specific pattern of neuropsychological functioning exists among children prenatally exposed to alcohol who received a diagnosis, versus exposed children who did not. We compared groups on domains of intellectual functioning, memory, attention, executive functioning, motor functioning, language/communication and achievement.
METHODS: One hundred and seventy children who were seen in the clinic between 2005 and 2009 were included in this study. Out of the total 170 children seen, 109 received an FASD diagnosis.
RESULTS: We identified a specific neuropsychological profile that typifies children diagnosed with an FASD versus those exposed prenatally to alcohol, who did not receive a diagnosis. Diagnosed children displayed a neuropsychological profile characterized by weaknesses in the areas of verbal reasoning, memory, overall language functioning, math reasoning and calculation. Groups did not differ on measures of attention or executive functioning.
CONCLUSION: The information gained from these analyses, are essential for informing best practices for diagnosis and treatment.

Entities:  

Mesh:

Year:  2013        PMID: 23513044

Source DB:  PubMed          Journal:  J Popul Ther Clin Pharmacol        ISSN: 2561-8741


  7 in total

Review 1.  Developmental consequences of fetal exposure to drugs: what we know and what we still must learn.

Authors:  Emily J Ross; Devon L Graham; Kelli M Money; Gregg D Stanwood
Journal:  Neuropsychopharmacology       Date:  2014-06-18       Impact factor: 7.853

2.  Adenylyl cylases 1 and 8 mediate select striatal-dependent behaviors and sensitivity to ethanol stimulation in the adolescent period following acute neonatal ethanol exposure.

Authors:  Laura L Susick; Jennifer L Lowing; Kelly E Bosse; Clara C Hildebrandt; Alexandria C Chrumka; Alana C Conti
Journal:  Behav Brain Res       Date:  2014-04-24       Impact factor: 3.332

Review 3.  Forty Years of Assessing Neurodevelopmental and Behavioral Effects of Prenatal Alcohol Exposure in Infants: What Have We Learned?

Authors:  Laura Garrison; Sarah Morley; Christina D Chambers; Ludmila N Bakhireva
Journal:  Alcohol Clin Exp Res       Date:  2019-07-03       Impact factor: 3.455

4.  Self-regulation therapy increases frontal gray matter in children with fetal alcohol spectrum disorder: evaluation by voxel-based morphometry.

Authors:  Debra W Soh; Jovanka Skocic; Kelly Nash; Sara Stevens; Gary R Turner; Joanne Rovet
Journal:  Front Hum Neurosci       Date:  2015-03-04       Impact factor: 3.169

5.  Cortical morphology in children with alcohol-related neurodevelopmental disorder.

Authors:  Meghna Rajaprakash; M Mallar Chakravarty; Jason P Lerch; Joanne Rovet
Journal:  Brain Behav       Date:  2013-11-27       Impact factor: 2.708

6.  Preliminary Findings that a Targeted Intervention Leads to Altered Brain Function in Children with Fetal Alcohol Spectrum Disorder.

Authors:  Kelly Nash; Sara Stevens; Hayyah Clairman; Joanne Rovet
Journal:  Brain Sci       Date:  2017-12-28

Review 7.  Neurodevelopmental profile of Fetal Alcohol Spectrum Disorder: A systematic review.

Authors:  Shannon Lange; Joanne Rovet; Jürgen Rehm; Svetlana Popova
Journal:  BMC Psychol       Date:  2017-06-23
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.