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Literature DB >> 23512703

Red-light-controlled protein-RNA crosslinking with a genetically encoded furan.

Abstract

Well red: A protein-RNA crosslinker has been genetically encoded that can be controlled with red light, thus offering high penetration depths in biological materials. This should enable the discovery and mapping of transient protein-RNA interactions and enable the design of peptide- and protein-based drugs for RNA-targeted photodynamic therapy.

Entities: Chemical

Mesh：

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Year: 2013 PMID： 23512703 DOI： 10.1002/anie.201300754

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

11 in total

Review 1. Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.

Authors: Wei Wan; Jeffery M Tharp; Wenshe R Liu
Journal: Biochim Biophys Acta Date: 2014-03-12

2. Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings.

Authors: Vanessa K Lacey; Gordon V Louie; Joseph P Noel; Lei Wang
Journal: Chembiochem Date: 2013-09-09 Impact factor: 3.164

Review 3. A molecular engineering toolbox for the structural biologist.

Authors: Galia T Debelouchina; Tom W Muir
Journal: Q Rev Biophys Date: 2017-01 Impact factor: 5.318

4. A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.

Authors: Andre H St Amant; Fengying Huang; Jia Lin; Keith Rickert; Vaheh Oganesyan; Daniel Lemen; Shenlan Mao; Jay Harper; Marcello Marelli; Herren Wu; Changshou Gao; Javier Read de Alaniz; R James Christie
Journal: Angew Chem Int Ed Engl Date: 2019-05-14 Impact factor: 15.336

Review 5. Genetic code expansion as a tool to study regulatory processes of transcription.

Authors: Moritz J Schmidt; Daniel Summerer
Journal: Front Chem Date: 2014-02-25 Impact factor: 5.221

6. Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

Authors: Yadagiri Kurra; Keturah A Odoi; Yan-Jiun Lee; Yanyan Yang; Tongxiang Lu; Steven E Wheeler; Jessica Torres-Kolbus; Alexander Deiters; Wenshe R Liu
Journal: Bioconjug Chem Date: 2014-09-04 Impact factor: 4.774

Red-light-controlled protein-RNA crosslinking with a genetically encoded furan.

Review 1. Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.

2. Expanding the library and substrate diversity of the pyrrolysyl-tRNA synthetase to incorporate unnatural amino acids containing conjugated rings.

Review 3. A molecular engineering toolbox for the structural biologist.

4. A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.

Review 5. Genetic code expansion as a tool to study regulatory processes of transcription.

6. Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

Review 7. Designing logical codon reassignment - Expanding the chemistry in biology.

8. Photoaffinity labeling of transcription factors by DNA-templated crosslinking.

9. Injectable Peptide Hydrogel Enables Integrated Tandem Enzymes' Superactivity for Cancer Therapy.

10. Equipping Coiled-Coil Peptide Dimers With Furan Warheads Reveals Novel Cross-Link Partners.