Literature DB >> 23508603

Enhanced communication skills and C-reactive protein point-of-care testing for respiratory tract infection: 3.5-year follow-up of a cluster randomized trial.

Jochen W L Cals1, Leon de Bock, Pieter-Jan H W Beckers, Nick A Francis, Rogier M Hopstaken, Kerenza Hood, Eefje G P M de Bont, Christopher C Butler, Geert-Jan Dinant.   

Abstract

PURPOSE: The purpose of the study was to assess the long-term effect of family physicians' use of C-reactive protein (CRP) point-of-care testing and/or physician training in enhanced communication skills on office visit rates and antibiotic prescriptions for patients with respiratory tract infections.
METHODS: We conducted a 3.5-year follow-up of a pragmatic, factorial, cluster-randomized controlled trial; 379 patients (20 family practices in the Netherlands) who visited their family physician for acute cough were enrolled in the trial and had follow-up data available (88% of original trial cohort). Main outcome measures were the average number of episodes of respiratory tract infections for which patients visited their family physician per patient per year (PPPY), and the percentage of the episodes for which patients were treated with antibiotics during follow-up.
RESULTS: The mean number of episodes of respiratory tract infections during follow-up was 0.40 PPPY in the CRP test group and 0.56 PPPY in the no CRP test group (P = .12). In the communication skills training group, there was a mean of 0.36 PPPY episodes of respiratory tract infections, and in the no training group the mean was 0.57 PPPY (P = .09). During follow-up 30.7% of all episodes of respiratory tract infection were treated with antibiotics in the CRP test group compared with 35.7% in the no test group (P = .36). Family physicians trained in communication skills treated 26.3% of all episodes of respiratory tract infection with antibiotics compared with 39.1% treated by family physicians without training in communication skills (P = .02)
CONCLUSIONS: Family physicians' use of CRP point-of-care testing and/or training in enhanced communication skills did not significantly affect office visit rates related to respiratory tract infections. Patients who saw a family physician trained in enhanced communication skills were prescribed significantly fewer antibiotics during episodes of respiratory tract infection in the subsequent 3.5 years.

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Year:  2013        PMID: 23508603      PMCID: PMC3601394          DOI: 10.1370/afm.1477

Source DB:  PubMed          Journal:  Ann Fam Med        ISSN: 1544-1709            Impact factor:   5.166


  28 in total

1.  Evidence based management of acute bronchitis; sustained competence of enhanced communication skills acquisition in general practice.

Authors:  Jochen W L Cals; Nicole A M Scheppers; Rogier M Hopstaken; Kerenza Hood; Geert-Jan Dinant; Henk Goettsch; Christopher C Butler
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2.  Systemic and upper and lower airway inflammation at exacerbation of chronic obstructive pulmonary disease.

Authors:  John R Hurst; Wayomi R Perera; Tom M A Wilkinson; Gavin C Donaldson; Jadwiga A Wedzicha
Journal:  Am J Respir Crit Care Med       Date:  2005-09-22       Impact factor: 21.405

3.  Evaluation of a rapid bedside test for the quantitative determination of C-reactive protein.

Authors:  Susanna Esposito; Elena Tremolati; Enrica Begliatti; Samantha Bosis; Laura Gualtieri; Nicola Principi
Journal:  Clin Chem Lab Med       Date:  2005       Impact factor: 3.694

4.  Outpatient antibiotic use in Europe and association with resistance: a cross-national database study.

Authors:  Herman Goossens; Matus Ferech; Robert Vander Stichele; Monique Elseviers
Journal:  Lancet       Date:  2005 Feb 12-18       Impact factor: 79.321

5.  Contributions of symptoms, signs, erythrocyte sedimentation rate, and C-reactive protein to a diagnosis of pneumonia in acute lower respiratory tract infection.

Authors:  R M Hopstaken; J W Muris; J A Knottnerus; A D Kester; P E Rinkens; G J Dinant
Journal:  Br J Gen Pract       Date:  2003-05       Impact factor: 5.386

6.  Labelling of acute respiratory illness: evidence of between-practitioner variation in the UK.

Authors:  Nigel Stocks; Tom Fahey
Journal:  Fam Pract       Date:  2002-08       Impact factor: 2.267

7.  Importance of patient pressure and perceived pressure and perceived medical need for investigations, referral, and prescribing in primary care: nested observational study.

Authors:  Paul Little; Martina Dorward; Greg Warner; Katharine Stephens; Jane Senior; Michael Moore
Journal:  BMJ       Date:  2004-02-13

8.  Effect of using an interactive booklet about childhood respiratory tract infections in primary care consultations on reconsulting and antibiotic prescribing: a cluster randomised controlled trial.

Authors:  Nick A Francis; Christopher C Butler; Kerenza Hood; Sharon Simpson; Fiona Wood; Jacqueline Nuttall
Journal:  BMJ       Date:  2009-07-29

9.  Effect of point of care testing for C reactive protein and training in communication skills on antibiotic use in lower respiratory tract infections: cluster randomised trial.

Authors:  Jochen W L Cals; Christopher C Butler; Rogier M Hopstaken; Kerenza Hood; Geert-Jan Dinant
Journal:  BMJ       Date:  2009-05-05

10.  The necessary shift from diagnostic to prognostic research.

Authors:  Geert-Jan G J Dinant; Frank F Buntinx; Chris C C Butler
Journal:  BMC Fam Pract       Date:  2007-09-13       Impact factor: 2.497

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  34 in total

1.  Verbal and non-verbal behaviour and patient perception of communication in primary care: an observational study.

Authors:  Paul Little; Peter White; Joanne Kelly; Hazel Everitt; Shkelzen Gashi; Annemieke Bikker; Stewart Mercer
Journal:  Br J Gen Pract       Date:  2015-06       Impact factor: 5.386

Review 2.  Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem.

Authors:  Carl Llor; Lars Bjerrum
Journal:  Ther Adv Drug Saf       Date:  2014-12

3.  Comparative effectiveness of three anxiolytics for acute respiratory infections: antibiotics, C-reactive protein point-of-care testing, and improved communication.

Authors:  Jeffrey A Linder
Journal:  J Gen Intern Med       Date:  2015-04       Impact factor: 5.128

4.  Incorrect inclusion of individual studies and methodological flaws in systematic review and meta-analysis.

Authors:  Rune Aabenhus; Jens-Ulrik S Jensen; Jochen Wl Cals
Journal:  Br J Gen Pract       Date:  2014-05       Impact factor: 5.386

5.  Antibiotic Prescribing for Acute Respiratory Tract Infections 12 Months After Communication and CRP Training: A Randomized Trial.

Authors:  Paul Little; Beth Stuart; Nick Francis; Elaine Douglas; Sarah Tonkin-Crine; Sibyl Anthierens; Jochen W L Cals; Hasse Melbye; Miriam Santer; Michael Moore; Samuel Coenen; Chris C Butler; Kerenza Hood; Mark Kelson; Maciek Godycki-Cwirko; Artur Mierzecki; Antoni Torres; Carl Llor; Melanie Davies; Mark Mullee; Gilly O'Reilly; Alike van der Velden; Adam W A Geraghty; Herman Goossens; Theo Verheij; Lucy Yardley
Journal:  Ann Fam Med       Date:  2019-03       Impact factor: 5.166

Review 6.  Can Patient-Provider Interpersonal Interventions Achieve the Quadruple Aim of Healthcare? A Systematic Review.

Authors:  Marie C Haverfield; Aaron Tierney; Rachel Schwartz; Michelle B Bass; Cati Brown-Johnson; Dani L Zionts; Nadia Safaeinili; Meredith Fischer; Jonathan G Shaw; Sonoo Thadaney; Gabriella Piccininni; Karl A Lorenz; Steven M Asch; Abraham Verghese; Donna M Zulman
Journal:  J Gen Intern Med       Date:  2020-01-09       Impact factor: 5.128

7.  Effects of a nudge-based antimicrobial stewardship program in a pediatric primary emergency medical center.

Authors:  Ayumi Shishido; Shogo Otake; Makoto Kimura; Shinya Tsuzuki; Akiko Fukuda; Akihito Ishida; Masashi Kasai; Yoshiki Kusama
Journal:  Eur J Pediatr       Date:  2021-02-08       Impact factor: 3.183

8.  Clinicians' views and experiences of interventions to enhance the quality of antibiotic prescribing for acute respiratory tract infections.

Authors:  Sibyl Anthierens; Sarah Tonkin-Crine; Jochen W Cals; Samuel Coenen; Lucy Yardley; Lucy Brookes-Howell; Patricia Fernandez-Vandellos; Jaroslaw Krawczyk; Maciek Godycki-Cwirko; Carl Llor; Christopher C Butler; Theo Verheij; Herman Goossens; Paul Little; Nick A Francis
Journal:  J Gen Intern Med       Date:  2014-11-06       Impact factor: 5.128

Review 9.  Association between point-of-care CRP testing and antibiotic prescribing in respiratory tract infections: a systematic review and meta-analysis of primary care studies.

Authors:  Yafang Huang; Rui Chen; Tao Wu; Xiaoming Wei; Aimin Guo
Journal:  Br J Gen Pract       Date:  2013-11       Impact factor: 5.386

Review 10.  Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews.

Authors:  Sarah Kg Tonkin-Crine; Pui San Tan; Oliver van Hecke; Kay Wang; Nia W Roberts; Amanda McCullough; Malene Plejdrup Hansen; Christopher C Butler; Chris B Del Mar
Journal:  Cochrane Database Syst Rev       Date:  2017-09-07
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