Literature DB >> 23507784

Realization of a poro-elastic ultrasound replica of pulmonary tissue.

Andrea Spinelli1, Bruna Vinci, Annalisa Tirella, Marco Matteucci, Luna Gargani, Arti Ahluwalia, Claudio Domenici, Eugenio Picano, Piero Chiarelli.   

Abstract

In this work we describe the fabrication of a biocompatible hydrophilic scaffold composed of cross-linked gelatin that mimics the porous three-dimensional structure of pulmonary tissue as well as its water content and mechanical properties. The lung replica also reproduces the characteristic sonographic signs of pulmonary interstitial syndrome, the B-lines or ultrasound lung comets.

Entities:  

Keywords:  B-lines; echographic signals; gelatin; hydrogels; lung replica; mechanical properties; porosity

Mesh:

Substances:

Year:  2012        PMID: 23507784      PMCID: PMC3849056          DOI: 10.4161/biom.19835

Source DB:  PubMed          Journal:  Biomatter        ISSN: 2159-2527


  10 in total

1.  Control of pore structure and size in freeze-dried collagen sponges.

Authors:  H Schoof; J Apel; I Heschel; G Rau
Journal:  J Biomed Mater Res       Date:  2001

2.  The number of alveoli in the human lung.

Authors:  Matthias Ochs; Jens R Nyengaard; Anja Jung; Lars Knudsen; Marion Voigt; Thorsten Wahlers; Joachim Richter; Hans Jørgen G Gundersen
Journal:  Am J Respir Crit Care Med       Date:  2003-09-25       Impact factor: 21.405

3.  Analysis of lung parenchyma as a parametric porous medium.

Authors:  Boris Lande; Wayne Mitzner
Journal:  J Appl Physiol (1985)       Date:  2006-06-01

4.  The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome.

Authors:  D Lichtenstein; G Mézière; P Biderman; A Gepner; O Barré
Journal:  Am J Respir Crit Care Med       Date:  1997-11       Impact factor: 21.405

5.  Mechanical and thermal properties of gelatin films at different degrees of glutaraldehyde crosslinking.

Authors:  A Bigi; G Cojazzi; S Panzavolta; K Rubini; N Roveri
Journal:  Biomaterials       Date:  2001-04       Impact factor: 12.479

6.  Formation of lung alveolar-like structures in collagen-glycosaminoglycan scaffolds in vitro.

Authors:  Patty Chen; Erika Marsilio; Ronald H Goldstein; Ioannis V Yannas; Myron Spector
Journal:  Tissue Eng       Date:  2005 Sep-Oct

7.  Letter: Correlation of echographic visualizability of tissue with biological composition and physiological state.

Authors:  S Fields; F Dunn
Journal:  J Acoust Soc Am       Date:  1973-09       Impact factor: 1.840

Review 8.  Ultrasound lung comets: a clinically useful sign of extravascular lung water.

Authors:  Eugenio Picano; Francesca Frassi; Eustachio Agricola; Suzana Gligorova; Luna Gargani; Gaetano Mottola
Journal:  J Am Soc Echocardiogr       Date:  2006-03       Impact factor: 5.251

9.  Crosslinked gelatin matrices: release of a random coil macromolecular solute.

Authors:  Jane W Mwangi; Clyde M Ofner
Journal:  Int J Pharm       Date:  2004-07-08       Impact factor: 5.875

10.  Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water.

Authors:  Zoltan Jambrik; Simonetta Monti; Vincenzo Coppola; Eustachio Agricola; Gaetano Mottola; Massimo Miniati; Eugenio Picano
Journal:  Am J Cardiol       Date:  2004-05-15       Impact factor: 2.778

  10 in total
  6 in total

1.  Decoupling the role of stiffness from other hydroxyapatite signalling cues in periosteal derived stem cell differentiation.

Authors:  Giorgio Mattei; Concetta Ferretti; Annalisa Tirella; Arti Ahluwalia; Monica Mattioli-Belmonte
Journal:  Sci Rep       Date:  2015-06-02       Impact factor: 4.379

Review 2.  Ultrasound of extravascular lung water: a new standard for pulmonary congestion.

Authors:  Eugenio Picano; Patricia A Pellikka
Journal:  Eur Heart J       Date:  2016-05-12       Impact factor: 29.983

3.  A multistep procedure to prepare pre-vascularized cardiac tissue constructs using adult stem sells, dynamic cell cultures, and porous scaffolds.

Authors:  Stefania Pagliari; Annalisa Tirella; Arti Ahluwalia; Sjoerd Duim; Marie-Josè Goumans; Takao Aoyagi; Giancarlo Forte
Journal:  Front Physiol       Date:  2014-06-03       Impact factor: 4.566

4.  Strain rate viscoelastic analysis of soft and highly hydrated biomaterials.

Authors:  A Tirella; G Mattei; A Ahluwalia
Journal:  J Biomed Mater Res A       Date:  2013-08-30       Impact factor: 4.396

5.  Determination of a potential quantitative measure of the state of the lung using lung ultrasound spectroscopy.

Authors:  Libertario Demi; Wim van Hoeve; Ruud J G van Sloun; Gino Soldati; Marcello Demi
Journal:  Sci Rep       Date:  2017-10-06       Impact factor: 4.379

6.  The Role of Transthoracic Ultrasound in the Study of Interstitial Lung Diseases: High-Resolution Computed Tomography Versus Ultrasound Patterns: Our Preliminary Experience.

Authors:  Donato Lacedonia; Giulia Scioscia; Angelamaria Giardinelli; Carla Maria Irene Quarato; Ennio Vincenzo Sassani; Maria Pia Foschino Barbaro; Federica Maci; Marco Sperandeo
Journal:  Diagnostics (Basel)       Date:  2021-03-04
  6 in total

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