| Literature DB >> 23507781 |
Abstract
Regeneration of myocardium through regenerative therapy and tissue engineering is appearing as a prospective treatment modality for patients with end-stage heart failure. Focusing on this area, this review highlights the new developments and challenges in the regeneration of myocardial tissue. The role of various cell sources, calcium ion and cytokine on the functional performance of regenerative therapy is discussed. The evolution of tissue engineering and the role of tissue matrix/scaffold, cell adhesion and vascularisation on tissue engineering of cardiac tissue implant are also discussed.Entities:
Keywords: end-stage cardiac failure; new developments and challenges; regenerative therapy; tissue engineering
Mesh:
Substances:
Year: 2012 PMID: 23507781 PMCID: PMC3849053 DOI: 10.4161/biom.19429
Source DB: PubMed Journal: Biomatter ISSN: 2159-2527