T Patterson1, C M Rapsey, P Glue. 1. Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, New Zealand. tess.patterson@otago.ac.nz
Abstract
BACKGROUND: There is conjecture regarding the profile of cognitive development over time in children with Down syndrome (DS). Characterising this profile would be valuable for the planning and assessment of intervention studies. METHOD: A systematic search of the literature from 1990 to the present was conducted to identify longitudinal data on cognitive trajectories in children with DS. RESULTS: Thirteen studies were identified: six assessed overall cognitive performance and seven assessed specific cognitive domains. Studies assessing IQ reported a decline across time. Studies assessing change in cognitive domains were, for the most part, not interpretable because of large age ranges in samples obscuring age-specific data. CONCLUSION: The current literature has only begun to describe typical cognitive developmental trajectories in children with DS; additional research is needed to clarify this topic.
BACKGROUND: There is conjecture regarding the profile of cognitive development over time in children with Down syndrome (DS). Characterising this profile would be valuable for the planning and assessment of intervention studies. METHOD: A systematic search of the literature from 1990 to the present was conducted to identify longitudinal data on cognitive trajectories in children with DS. RESULTS: Thirteen studies were identified: six assessed overall cognitive performance and seven assessed specific cognitive domains. Studies assessing IQ reported a decline across time. Studies assessing change in cognitive domains were, for the most part, not interpretable because of large age ranges in samples obscuring age-specific data. CONCLUSION: The current literature has only begun to describe typical cognitive developmental trajectories in children with DS; additional research is needed to clarify this topic.
Authors: Jacob Vorstman; Elemi J Breetvelt; Ania M Fiksinski; Carrie E Bearden; Anne S Bassett; René S Kahn; Janneke R Zinkstok; Stephen R Hooper; Wanda Tempelaar; Donna McDonald-McGinn; Ann Swillen; Beverly Emanuel; Bernice Morrow; Raquel Gur; Eva Chow; Marianne van den Bree; Joris Vermeesch; Stephen Warren; Michael Owen; Therese van Amelsvoort; Stephan Eliez; Doron Gothelf; Celso Arango; Wendy Kates; Tony Simon; Kieran Murphy; Gabriela Repetto; Damian Heine Suner; Stefano Vicari; Joseph Cubells; Marco Armando; Nicole Philip; Linda Campbell; Sixto Garcia-Minaur; Maude Schneider; Vandana Shashi Journal: Neuropsychopharmacology Date: 2021-03-29 Impact factor: 8.294
Authors: Renée J Zwanenburg; Selma A J Ruiter; Edwin R van den Heuvel; Boudien C T Flapper; Conny M A Van Ravenswaaij-Arts Journal: J Neurodev Disord Date: 2016-04-26 Impact factor: 4.025