Literature DB >> 23494947

"Clickable" hydrosoluble PEGylated cryptophane as a universal platform for 129Xe magnetic resonance imaging biosensors.

Léa Delacour1, Naoko Kotera, Ténin Traoré, Sébastien Garcia-Argote, Céline Puente, François Leteurtre, Edmond Gravel, Nawal Tassali, Céline Boutin, Estelle Léonce, Yves Boulard, Patrick Berthault, Bernard Rousseau.   

Abstract

We describe the synthesis of a highly water-soluble cryptophane 1 that can be seen as a universal platform for the construction of (129)Xe magnetic resonance imaging (MRI)-based biosensors. Compound 1 is easily functionalized by Huisgen cycloaddition and exhibits excellent xenon-encapsulation properties. In addition, 1 is nontoxic at the concentrations typically used for hyperpolarized (129)Xe MRI.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23494947     DOI： 10.1002/chem.201204218

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  6 in total

1.  Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution.

Authors:  Qingbin Zeng; Binglin Bie; Qianni Guo; Yaping Yuan; Qi Han; Xiaocang Han; Mingwei Chen; Xu Zhang; Yunhuang Yang; Maili Liu; Pan Liu; Hexiang Deng; Xin Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2020-07-13       Impact factor: 11.205

2.  Development of an antibody-based, modular biosensor for 129Xe NMR molecular imaging of cells at nanomolar concentrations.

Authors:  Honor M Rose; Christopher Witte; Federica Rossella; Stefan Klippel; Christian Freund; Leif Schröder
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-28       Impact factor: 11.205

Review 3.  Hyperpolarized and inert gas MRI: the future.

Authors:  Marcus J Couch; Barbara Blasiak; Boguslaw Tomanek; Alexei V Ouriadov; Matthew S Fox; Krista M Dowhos; Mitchell S Albert
Journal:  Mol Imaging Biol       Date:  2015-04       Impact factor: 3.488

4.  NMR hyperpolarization techniques for biomedicine.

Authors:  Panayiotis Nikolaou; Boyd M Goodson; Eduard Y Chekmenev
Journal:  Chemistry       Date:  2014-12-03       Impact factor: 5.236

Review 5.  Molecular Sensing with Host Systems for Hyperpolarized 129Xe.

Authors:  Jabadurai Jayapaul; Leif Schröder
Journal:  Molecules       Date:  2020-10-11       Impact factor: 4.411

6.  Cryptophane-xenon complexes for 129Xe MRI applications.

Authors:  Serge D Zemerov; Ivan J Dmochowski
Journal:  RSC Adv       Date:  2021-02-17       Impact factor: 3.361
  6 in total

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