Literature DB >> 23484828

Long-term outcomes in elderly survivors of in-hospital cardiac arrest.

Paul S Chan1, Brahmajee K Nallamothu, Harlan M Krumholz, John A Spertus, Yan Li, Bradley G Hammill, Lesley H Curtis.   

Abstract

BACKGROUND: Little is known about the long-term outcomes in elderly survivors of in-hospital cardiac arrest. We determined rates of long-term survival and readmission among survivors of in-hospital cardiac arrest and examined whether these outcomes differed according to demographic characteristics and neurologic status at discharge.
METHODS: We linked data from a national registry of inpatient cardiac arrests with Medicare files and identified 6972 adults, 65 years of age or older, who were discharged from the hospital after surviving an in-hospital cardiac arrest between 2000 and 2008. Predictors of 1-year survival and of readmission to the hospital were examined.
RESULTS: One year after hospital discharge, 58.5% of the patients were alive, and 34.4% had not been readmitted to the hospital. The risk-adjusted rate of 1-year survival was lower among older patients than among younger patients (63.7%, 58.6%, and 49.7% among patients 65 to 74, 75 to 84, and ≥85 years of age, respectively; P<0.001), among men than among women (58.6% vs. 60.9%, P=0.03), and among black patients than among white patients (52.5% vs. 60.4%, P=0.001). The risk-adjusted rate of 1-year survival was 72.8% among patients with mild or no neurologic disability at discharge, as compared with 61.1% among patients with moderate neurologic disability, 42.2% among those with severe neurologic disability, and 10.2% among those in a coma or vegetative state (P<0.001 for all comparisons). Moreover, 1-year readmission rates were higher among patients who were black, those who were women, and those who had substantial neurologic disability (P<0.05 for all comparisons). These differences in survival and readmission rates persisted at 2 years. At 3 years, the rate of survival among survivors of in-hospital cardiac arrest was similar to that of patients who had been hospitalized with heart failure and were discharged alive (43.5% and 44.9%, respectively; risk ratio, 0.98; 95% confidence interval, 0.95 to 1.02; P=0.35).
CONCLUSIONS: Among elderly survivors of in-hospital cardiac arrest, nearly 60% were alive at 1 year, and the rate of 3-year survival was similar to that among patients with heart failure. Survival and readmission rates differed according to the demographic characteristics of the patients and neurologic status at discharge. (Funded by the American Heart Association and the National Heart, Lung, and Blood Institute.).

Entities:  

Mesh:

Year:  2013        PMID: 23484828      PMCID: PMC3652256          DOI: 10.1056/NEJMoa1200657

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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3.  Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association.

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4.  Women of child-bearing age have better inhospital cardiac arrest survival outcomes than do equal-aged men.

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5.  Predictors of survival after cardiac or respiratory arrest in critical care units.

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7.  Long-term survival and residual hazard after in-hospital cardiac arrest.

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8.  Survival from in-hospital cardiac arrest during nights and weekends.

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9.  Delayed time to defibrillation after in-hospital cardiac arrest.

Authors:  Paul S Chan; Harlan M Krumholz; Graham Nichol; Brahmajee K Nallamothu
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10.  Linking inpatient clinical registry data to Medicare claims data using indirect identifiers.

Authors:  Bradley G Hammill; Adrian F Hernandez; Eric D Peterson; Gregg C Fonarow; Kevin A Schulman; Lesley H Curtis
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  50 in total

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Review 2.  Healthcare disparities in critical illness.

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4.  Association Between Prompt Defibrillation and Epinephrine Treatment With Long-Term Survival After In-Hospital Cardiac Arrest.

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5.  Alignment of Do-Not-Resuscitate Status With Patients' Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest.

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6.  Administrative Codes for Capturing In-Hospital Cardiac Arrest.

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7.  Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest.

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Review 8.  Post-resuscitation care following out-of-hospital and in-hospital cardiac arrest.

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10.  Long-term outcomes after in-hospital CPR in older adults with chronic illness.

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