OBJECTIVE: To evaluate the effectiveness of a home-based rehabilitation of balance using the Nintendo Wii Balance Board System (WBBS) in patients affected by multiple sclerosis (MS). METHODS: In this 24-week, randomized, 2-period crossover pilot study, 36 patients having an objective balance disorder were randomly assigned in a 1:1 ratio to 2 counterbalanced arms. Group A started a 12-week period of home-based WBBS training followed by a 12-week period without any intervention; group B received the treatment in reverse order. As endpoints, we considered the mean difference (compared with baseline) in force platform measures (i.e., the displacement of body center of pressure in 30 seconds), 4-step square test (FSST), 25-foot timed walking test (25-FWT), and 29-item MS Impact Scale (MSIS-29), as evaluated after 12 weeks and at the end of the 24-week study period. RESULTS: The 2 groups did not differ in baseline characteristics. Repeated-measures analyses of variance showed significant time × treatment effects, indicating that WBBS was effective in ameliorating force platform measures (F = 4.608, P = .016), FSST (F = 3.745, P = .034), 25-FWT (F = 3.339, P = .048), and MSIS-29 (F = 4.282, P = .023). Five adverse events attributable to the WBSS training (knee or low back pain) were recorded, but only 1 patient had to retire from the study. CONCLUSION: A home-based WBBS training might potentially provide an effective, engaging, balance rehabilitation solution for people with MS. However, the risk of WBBS training-related injuries should be carefully balanced with benefits. Further studies, including cost-effectiveness analyses, are warranted to establish whether WBBS may be useful in the home setting.
RCT Entities:
OBJECTIVE: To evaluate the effectiveness of a home-based rehabilitation of balance using the Nintendo Wii Balance Board System (WBBS) in patients affected by multiple sclerosis (MS). METHODS: In this 24-week, randomized, 2-period crossover pilot study, 36 patients having an objective balance disorder were randomly assigned in a 1:1 ratio to 2 counterbalanced arms. Group A started a 12-week period of home-based WBBS training followed by a 12-week period without any intervention; group B received the treatment in reverse order. As endpoints, we considered the mean difference (compared with baseline) in force platform measures (i.e., the displacement of body center of pressure in 30 seconds), 4-step square test (FSST), 25-foot timed walking test (25-FWT), and 29-item MS Impact Scale (MSIS-29), as evaluated after 12 weeks and at the end of the 24-week study period. RESULTS: The 2 groups did not differ in baseline characteristics. Repeated-measures analyses of variance showed significant time × treatment effects, indicating that WBBS was effective in ameliorating force platform measures (F = 4.608, P = .016), FSST (F = 3.745, P = .034), 25-FWT (F = 3.339, P = .048), and MSIS-29 (F = 4.282, P = .023). Five adverse events attributable to the WBSS training (knee or low back pain) were recorded, but only 1 patient had to retire from the study. CONCLUSION: A home-based WBBS training might potentially provide an effective, engaging, balance rehabilitation solution for people with MS. However, the risk of WBBS training-related injuries should be carefully balanced with benefits. Further studies, including cost-effectiveness analyses, are warranted to establish whether WBBS may be useful in the home setting.
Authors: Weihong Yuan; Karen Harpster; Blaise V Jones; Joshua S Shimony; Robert C McKinstry; Nicole Weckherlin; Stephanie S Powell; Holly Barnard; Jack Engsberg; Darren S Kadis; Jonathan Dodd; Mekibib Altaye; David D Limbrick; Scott K Holland; Sarah M Simpson; Sarah Bidwell; Francesco T Mangano Journal: Neuropediatrics Date: 2016-07-20 Impact factor: 1.947
Authors: Tian Bao; Brooke N Klatt; Susan L Whitney; Kathleen H Sienko; Jenna Wiens Journal: IEEE Trans Neural Syst Rehabil Eng Date: 2019-01-04 Impact factor: 3.802
Authors: Weihong Yuan; Shari L Wade; Catherine Quatman-Yates; Jason A Hugentobler; Paul J Gubanich; Brad G Kurowski Journal: J Head Trauma Rehabil Date: 2017 Nov/Dec Impact factor: 2.710
Authors: Ruopeng Sun; Yaejin Moon; Ryan S McGinnis; Kirsten Seagers; Robert W Motl; Nirav Sheth; John A Wright; Roozbeh Ghaffari; Shyamal Patel; Jacob J Sosnoff Journal: Digit Biomark Date: 2018-01-23