Cameron N McIntosh1. 1. National Crime Prevention Centre, Public Safety Canada, 269 Laurier Avenue West, Ottawa, ON, K1A 0P8, Canada, cameron.mcintosh@ps-sp.gc.ca.
Abstract
OBJECTIVES: This article is a brief commentary in response to "van Leeuwen et al. (Qual Life Res 21:1499-1508, 2012)" METHODS AND RESULTS: The commentary argues that in the context of mixture modeling, assigning individuals to specific subgroups for conducting a secondary set of analyses ignores the original uncertainty in group membership, thereby biasing any subsequent results and inference. CONCLUSIONS: Alternative approaches to subgroup analysis that attempt to preserve uncertainty in group membership are discussed and illustrated.
OBJECTIVES: This article is a brief commentary in response to "van Leeuwen et al. (Qual Life Res 21:1499-1508, 2012)" METHODS AND RESULTS: The commentary argues that in the context of mixture modeling, assigning individuals to specific subgroups for conducting a secondary set of analyses ignores the original uncertainty in group membership, thereby biasing any subsequent results and inference. CONCLUSIONS: Alternative approaches to subgroup analysis that attempt to preserve uncertainty in group membership are discussed and illustrated.
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