Literature DB >> 23472820

Atkamine: a new pyrroloiminoquinone scaffold from the cold water Aleutian Islands Latrunculia sponge.

Yike Zou1, Mark T Hamann.   

Abstract

A new pyrroloiminoquinone alkaloid, named atkamine, with an unusual scaffold was discovered from a cold, deep water Alaskan sponge Latrunculia sp. collected from the Aleutian Islands. Olefin metathesis was utilized to determine the location of the double bond in the hydrocarbon chain. The absolute configuration was determined by using computational approaches combing with the ECD (electronic circular dichroism) spectroscopy.

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Year:  2013        PMID： 23472820      PMCID： PMC4137554          DOI： 10.1021/ol400294v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  12 in total

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5.  Influence of quinone methide reactivity on the alkylation of thiol and amino groups in proteins: studies utilizing amino acid and peptide models.

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7.  A molecular caliper mechanism for determining very long-chain fatty acid length.

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8.  13C-NMR of double and triple bond carbon atoms of unsaturated fatty acid methyl esters.

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Journal:  Chem Phys Lipids       Date:  1977-01       Impact factor: 3.329

9.  Fatty acids. Part 50. 13C nuclear magnetic resonance studies of olefinic fatty acids and esters.

Authors:  F D Gunstone; M R Polard; C M Scrimgeour; H S Vedanayagam
Journal:  Chem Phys Lipids       Date:  1977-01       Impact factor: 3.329

10.  New 17-methyl-13-octadecenoic and 3,16-docosadienoic acids from the sponge Polymastia penicillus.

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4.  New Discorhabdin B Dimers with Anticancer Activity from the Antarctic Deep-Sea Sponge Latrunculia biformis.

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Review 5.  Chemistry, Chemotaxonomy and Biological Activity of the Latrunculid Sponges (Order Poecilosclerida, Family Latrunculiidae).

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6.  Magnificines A and B, Antimicrobial Marine Alkaloids Featuring a Tetrahydrooxazolo[3,2-a]azepine-2,5(3H,6H)-dione Backbone from the Red Sea Sponge Negombata magnifica.

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7.  New hippolide derivatives with protein tyrosine phosphatase 1B inhibitory activity from the marine sponge Hippospongia lachne.

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8.  Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product.

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