Literature DB >> 23471553

Cyanoacrylate microbial sealant may reduce the prevalence of positive cultures in revision shoulder arthroplasty.

Adam J Lorenzetti1, Montri D Wongworawat, Christopher M Jobe, Wesley P Phipatanakul.   

Abstract

BACKGROUND: Cyanoacrylate-based, microbial sealant is an adhesive skin barrier designed to prevent bacterial contamination in surgical wounds. This type of adhesive barrier could have use in decreasing the incidence of positive cultures and subsequent infection in shoulder arthroplasty. QUESTIONS/PURPOSES: We therefore evaluated whether cyanoacrylate microbial sealant reduced the positive intraoperative culture rates in revision shoulder arthroplasty.
METHODS: We retrospectively reviewed 55 patients who underwent revision shoulder arthroplasties. Intraoperative aerobic and anaerobic deep tissue culture results taken during the revisions were compared. Cultures were taken of the deep synovial tissue lining the prosthesis. Patients were divided into two groups: those who underwent standard preparations with adhesive, iodine-barrier drapes (Group SP) and those who had placement of cyanoacrylate microbial sealant in addition to the standard prep (Group MS).
RESULTS: The prevalence of cases with positive cultures was 18% (seven of 40) in Group SP compared with 7% (one of 15) in Group MS. The prevalence of positive, anaerobic Propionibacterium acnes cultures was 13% in Group SP compared with 7% in Group MS. The prevalence of infections confirmed at revision surgery was 8% in Group SP versus 0% in Group MS.
CONCLUSIONS: Our observations suggest application of a cyanoacrylate microbial sealant may reduce the prevalence of positive cultures and thereby subsequent infections in revision shoulder arthroplasties. LEVEL OF EVIDENCE: Level III, retrospective cohort study. See Guidelines for Authors for a complete description of levels of evidence.

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Year:  2013        PMID: 23471553      PMCID: PMC3773134          DOI: 10.1007/s11999-013-2854-5

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  21 in total

1.  Infection after mini-open rotator cuff repair.

Authors:  Mauricio F Herrera; Greg Bauer; Fletcher Reynolds; Richard M Wilk; Louis U Bigliani; William N Levine
Journal:  J Shoulder Elbow Surg       Date:  2002 Nov-Dec       Impact factor: 3.019

2.  Revision shoulder arthroplasty with positive intraoperative cultures: the value of preoperative studies and intraoperative histology.

Authors:  Mark S Topolski; Patrick Y K Chin; John W Sperling; Robert H Cofield
Journal:  J Shoulder Elbow Surg       Date:  2006 Jul-Aug       Impact factor: 3.019

3.  Cyanoacrylate for wound closure in prosthetic vascular graft surgery to prevent infections through contamination.

Authors:  Murat Aksoy; Erhan Turnadere; Kemal Ayalp; Murat Kayabali; Bulent Ertugrul; Levent Bilgic
Journal:  Surg Today       Date:  2006       Impact factor: 2.549

4.  Effectiveness of antimicrobial incise drapes versus cyanoacrylate barrier preparations for surgical sites.

Authors:  Sepehr Bady; Montri D Wongworawat
Journal:  Clin Orthop Relat Res       Date:  2009-03-10       Impact factor: 4.176

5.  Propionibacterium acnes infection after shoulder arthroplasty: a diagnostic challenge.

Authors:  Christopher C Dodson; Edward V Craig; Frank A Cordasco; David M Dines; Joshua S Dines; Edward Dicarlo; Barry D Brause; Russell F Warren
Journal:  J Shoulder Elbow Surg       Date:  2009-11-01       Impact factor: 3.019

Review 6.  Use of the reverse shoulder prosthesis for the treatment of failed hemiarthroplasty in patients with glenohumeral arthritis and rotator cuff deficiency.

Authors:  J C Levy; N Virani; D Pupello; M Frankle
Journal:  J Bone Joint Surg Br       Date:  2007-02

7.  Significant reduction in incidence of wound contamination by skin flora through use of microbial sealant.

Authors:  Shirin Towfigh; William G Cheadle; Stephen F Lowry; Mark A Malangoni; Samuel E Wilson
Journal:  Arch Surg       Date:  2008-09

8.  Clinical meaning of unexpected positive cultures (UPC) in revision shoulder arthroplasty.

Authors:  Antonio M Foruria; Tyler J Fox; John W Sperling; Robert H Cofield
Journal:  J Shoulder Elbow Surg       Date:  2012-09-13       Impact factor: 3.019

9.  Positive culture rate in revision shoulder arthroplasty.

Authors:  James D Kelly; E Rhett Hobgood
Journal:  Clin Orthop Relat Res       Date:  2009-05-12       Impact factor: 4.176

10.  Propionibacterium acnes colonization of the human shoulder.

Authors:  Amar Patel; Ryan P Calfee; Matthew Plante; Staci A Fischer; Andrew Green
Journal:  J Shoulder Elbow Surg       Date:  2009-04-11       Impact factor: 3.019

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  5 in total

1.  Management of Propionibacterium acnes infection after shoulder surgery.

Authors:  David Saper; Nina Capiro; Richard Ma; Xinning Li
Journal:  Curr Rev Musculoskelet Med       Date:  2015-03

Review 2.  Scoping review: Diagnosis and management of periprosthetic joint infection in shoulder arthroplasty.

Authors:  Anthony Egglestone; Helen Ingoe; Jonathan Rees; Michael Thomas; Richard Jeavons; Amar Rangan
Journal:  Shoulder Elbow       Date:  2018-07-25

Review 3.  Propionibacterium acnes infection after shoulder surgery.

Authors:  Benjamin K Kadler; Saurabh S Mehta; Lennard Funk
Journal:  Int J Shoulder Surg       Date:  2015 Oct-Dec

4.  Propionibacterium acnes infections in patients with idiopathic scoliosis: a case-control study and review of the literature.

Authors:  I Swarup; J Gruskay; M Price; J Yang; J Blanco; S Perlman; R Widmann
Journal:  J Child Orthop       Date:  2018-04-01       Impact factor: 1.548

Review 5.  Lack of level I evidence on how to prevent infection after elective shoulder surgery.

Authors:  Carola F Eck; Julie A Neumann; Orr Limpisvasti; Christopher R Adams
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-01-16       Impact factor: 4.114

  5 in total

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