Literature DB >> 23470748

Synthetic and structure-activity relationship studies on bioactive natural products.

Kouji Kuramochi1.   

Abstract

This review summarizes our research into the synthesis and structure-activity relationships of epolactaene, neoechinulin A, plakevulin A, pseudodeflectusin and ustusorane C. These natural products are attractive in view of their apoptosis-inducing activity, cytoprotective activity against peroxynitrite, inhibitory activity against DNA polymerases, and cytotoxicity in cancer cells.

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Year:  2013        PMID： 23470748     DOI： 10.1271/bbb.120884

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  3 in total

1.  Euvesperins A and B, new circumventors of arbekacin resistance in MRSA, produced by Metarhizium sp. FKI-7236.

Authors:  Mayu Shiina; Takuya Suga; Yukihiro Asami; Kenichi Nonaka; Masato Iwatsuki; Satoshi Omura; Kazuro Shiomi
Journal:  J Antibiot (Tokyo)       Date:  2016-01-13       Impact factor: 2.649

2.  Nature is the best source of anticancer drugs: Indexing natural products for their anticancer bioactivity.

Authors:  Anwar Rayan; Jamal Raiyn; Mizied Falah
Journal:  PLoS One       Date:  2017-11-09       Impact factor: 3.240

3.  Palladium-Catalyzed Aminocyclization-Coupling Cascades: Preparation of Dehydrotryptophan Derivatives and Computational Study.

Authors:  Belén Vaz; Claudio Martínez; Francisco Cruz; J Gabriel Denis; Ángel R de Lera; José M Aurrecoechea; Rosana Álvarez
Journal:  J Org Chem       Date:  2021-06-14       Impact factor: 4.354
  3 in total

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