Literature DB >> 23467398

Synthesis of Substituted Isatins.

Larry L Klein1, Michael D Tufano.   

Abstract

Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.

Entities:  

Keywords:  Sandmeyer isatin synthesis; isatin; oximinoacetanilides

Year:  2012        PMID： 23467398      PMCID： PMC3586330          DOI： 10.1016/j.tetlet.2012.12.035

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  7 in total

1.  The mechanism of Sandmeyer's cyclization reaction by electrospray ionization mass spectrometry.

Authors:  Bárbara V Silva; Flávio A Violante; Angelo C Pinto; Leonardo S Santos
Journal:  Rapid Commun Mass Spectrom       Date:  2011-02-15       Impact factor: 2.419

2.  Serotonergic effects of isatin: an endogenous MAO inhibitor related to tribulin.

Authors:  I M McIntyre; T R Norman
Journal:  J Neural Transm Gen Sect       Date:  1990

3.  alpha-Alkoximino acids.

Authors:  K L WATERS; W H HARTUNG
Journal:  J Org Chem       Date:  1947-05       Impact factor: 4.354

4.  (E)-(methyloxyimino)acetamides as analogues of neuroleptic benzamides: synthesis and D2-dopaminergic binding affinity.

Authors:  A Lapucci; M Macchia; E Orlandini; F Romagnoli; A Rossello; G Chiellini; P Cozzini; P Domiano
Journal:  Farmaco       Date:  1996-01

5.  Nonquaternary reactivators for organophosphate-inhibited cholinesterases.

Authors:  Jarosław Kalisiak; Erik C Ralph; John R Cashman
Journal:  J Med Chem       Date:  2011-12-29       Impact factor: 7.446

6.  Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs.

Authors:  Dharmarajan Sriram; Perumal Yogeeswari; Gayatri Gopal
Journal:  Eur J Med Chem       Date:  2005-08-29       Impact factor: 6.514

7.  Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids.

Authors:  G W Rewcastle; G J Atwell; Z A Li; B C Baguley; W A Denny
Journal:  J Med Chem       Date:  1991-01       Impact factor: 7.446
  7 in total

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