Literature DB >> 23466562

Stemformatics: visualisation and sharing of stem cell gene expression.

Christine A Wells1, Rowland Mosbergen, Othmar Korn, Jarny Choi, Nick Seidenman, Nicholas A Matigian, Alejandra M Vitale, Jill Shepherd.   

Abstract

Genome-scale technologies are increasingly adopted by the stem cell research community, because of the potential to uncover the molecular events most informative about a stem cell state. These technologies also present enormous challenges around the sharing and visualisation of data derived from different laboratories or under different experimental conditions. Stemformatics is an easy to use, publicly accessible portal that hosts a large collection of exemplar stem cell data. It provides fast visualisation of gene expression across a range of mouse and human datasets, with transparent links back to the original studies. One difficulty in the analysis of stem cell signatures is the paucity of public pathways/gene lists relevant to stem cell or developmental biology. Stemformatics provides a simple mechanism to create, share and analyse gene sets, providing a repository of community-annotated stem cell gene lists that are informative about pathways, lineage commitment, and common technical artefacts. Stemformatics can be accessed at stemformatics.org. Crown
Copyright © 2012. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 23466562     DOI: 10.1016/j.scr.2012.12.003

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN: 1873-5061            Impact factor:   2.020


  37 in total

1.  Signaling involved in stem cell reprogramming and differentiation.

Authors:  Shihori Tanabe
Journal:  World J Stem Cells       Date:  2015-08-26       Impact factor: 5.326

Review 2.  Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?

Authors:  Cheryl Filippich; Ernst J Wolvetang; Bryan J Mowry
Journal:  Schizophr Bull       Date:  2013-07-24       Impact factor: 9.306

3.  Genome-wide characterization of the routes to pluripotency.

Authors:  Samer M I Hussein; Mira C Puri; Peter D Tonge; Marco Benevento; Andrew J Corso; Jennifer L Clancy; Rowland Mosbergen; Mira Li; Dong-Sung Lee; Nicole Cloonan; David L A Wood; Javier Munoz; Robert Middleton; Othmar Korn; Hardip R Patel; Carl A White; Jong-Yeon Shin; Maely E Gauthier; Kim-Anh Lê Cao; Jong-Il Kim; Jessica C Mar; Nika Shakiba; William Ritchie; John E J Rasko; Sean M Grimmond; Peter W Zandstra; Christine A Wells; Thomas Preiss; Jeong-Sun Seo; Albert J R Heck; Ian M Rogers; Andras Nagy
Journal:  Nature       Date:  2014-12-11       Impact factor: 49.962

Review 4.  Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies.

Authors:  Farshid Guilak; Lara Pferdehirt; Alison K Ross; Yun-Rak Choi; KelseyH Collins; Robert J Nims; Dakota B Katz; Molly Klimak; Suzanne Tabbaa; Christine T N Pham
Journal:  J Orthop Res       Date:  2019-05-02       Impact factor: 3.494

5.  Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming.

Authors:  Xiaodong Liu; Christian M Nefzger; Fernando J Rossello; Joseph Chen; Anja S Knaupp; Jaber Firas; Ethan Ford; Jahnvi Pflueger; Jacob M Paynter; Hun S Chy; Carmel M O'Brien; Cheng Huang; Ketan Mishra; Margeaux Hodgson-Garms; Natasha Jansz; Sarah M Williams; Marnie E Blewitt; Susan K Nilsson; Ralf B Schittenhelm; Andrew L Laslett; Ryan Lister; Jose M Polo
Journal:  Nat Methods       Date:  2017-09-25       Impact factor: 28.547

6.  The Role of the Microglial Cx3cr1 Pathway in the Postnatal Maturation of Retinal Photoreceptors.

Authors:  Andrew I Jobling; Michelle Waugh; Kirstan A Vessey; Joanna A Phipps; Lidia Trogrlic; Una Greferath; Samuel A Mills; Zhi L Tan; Michelle M Ward; Erica L Fletcher
Journal:  J Neurosci       Date:  2018-04-18       Impact factor: 6.167

7.  Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

Authors:  Clayton E Friedman; Quan Nguyen; Samuel W Lukowski; Abbigail Helfer; Han Sheng Chiu; Jason Miklas; Shiri Levy; Shengbao Suo; Jing-Dong Jackie Han; Pierre Osteil; Guangdun Peng; Naihe Jing; Greg J Baillie; Anne Senabouth; Angelika N Christ; Timothy J Bruxner; Charles E Murry; Emily S Wong; Jun Ding; Yuliang Wang; James Hudson; Hannele Ruohola-Baker; Ziv Bar-Joseph; Patrick P L Tam; Joseph E Powell; Nathan J Palpant
Journal:  Cell Stem Cell       Date:  2018-10-04       Impact factor: 24.633

8.  Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern.

Authors:  Nicholas Matigian; Gary Brooke; Faten Zaibak; Tony Rossetti; Katarina Kollar; Rebecca Pelekanos; Celena Heazlewood; Alan Mackay-Sim; Christine A Wells; Kerry Atkinson
Journal:  Genom Data       Date:  2014-11-28

9.  Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: Gestational age versus niche.

Authors:  Jennifer M Ryan; Nicholas Matigian; Rebecca A Pelekanos; Samuel Jesuadian; Christine A Wells; Nicholas M Fisk
Journal:  Genom Data       Date:  2014-10-25

10.  An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator.

Authors:  Dong-Sung Lee; Jong-Yeon Shin; Peter D Tonge; Mira C Puri; Seungbok Lee; Hansoo Park; Won-Chul Lee; Samer M I Hussein; Thomas Bleazard; Ji-Young Yun; Jihye Kim; Mira Li; Nicole Cloonan; David Wood; Jennifer L Clancy; Rowland Mosbergen; Jae-Hyuk Yi; Kap-Seok Yang; Hyungtae Kim; Hwanseok Rhee; Christine A Wells; Thomas Preiss; Sean M Grimmond; Ian M Rogers; Andras Nagy; Jeong-Sun Seo
Journal:  Nat Commun       Date:  2014-12-10       Impact factor: 14.919

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