Literature DB >> 23465953

Cell cultured chondrocyte implantation and scaffold techniques for osteochondral talar lesions.

Ben Johnson1, Caroline Lever, Sally Roberts, James Richardson, Helen McCarthy, Paul Harrison, Patrick Laing, Nilesh Makwana.   

Abstract

Cell cultured techniques have gained interest and popularity in osteochondral defects because, unlike bone marrow stimulation methods, where fibrocartilage fills the defect, they allow for the regeneration of "hyaline-like cartilage" with better stiffness, resilience, and wear characteristics. Osteochondral defects in the ankle are a rare but challenging problem to treat in young active patients. If left alone, they can cause pain and reduced function and risk progressive degenerative changes in the joint. Clinical results of cell cultured and scaffold technology in the ankle, although still limited by small studies and midterm follow-up, are certainly encouraging.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23465953     DOI: 10.1016/j.fcl.2012.12.008

Source DB:  PubMed          Journal:  Foot Ankle Clin        ISSN: 1083-7515            Impact factor:   1.653


  8 in total

1.  Simultaneous Treatment of Osteochondral Lesion Does Not Affect the Mid- to Long-Term Outcomes of Ligament Repair for Acute Ankle Sprain: A Retrospective Comparative Study with a 3-11-Year Follow-up.

Authors:  Ming-Ze Du; Tong Su; Yan-Fang Jiang; Chen Jiao; Qin-Wei Guo; Yue-Lin Hu; Dong Jiang
Journal:  Front Surg       Date:  2022-05-09

Review 2.  Current concepts: tissue engineering and regenerative medicine applications in the ankle joint.

Authors:  S I Correia; H Pereira; J Silva-Correia; C N Van Dijk; J Espregueira-Mendes; J M Oliveira; R L Reis
Journal:  J R Soc Interface       Date:  2013-12-18       Impact factor: 4.118

Review 3.  Diagnosis and treatment of osteochondral lesions of the ankle: current concepts.

Authors:  Marcelo Pires Prado; John G Kennedy; Fernando Raduan; Caio Nery
Journal:  Rev Bras Ortop       Date:  2016-08-17

4.  Scaffolds based therapy for osteochondral lesions of the talus: A systematic review.

Authors:  Yoshiharu Shimozono; Youichi Yasui; Andrew W Ross; Wataru Miyamoto; John G Kennedy
Journal:  World J Orthop       Date:  2017-10-18

Review 5.  No superior surgical treatment for secondary osteochondral defects of the talus.

Authors:  Kaj T A Lambers; Jari Dahmen; Mikel L Reilingh; Christiaan J A van Bergen; Sjoerd A S Stufkens; Gino M M J Kerkhoffs
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-07       Impact factor: 4.342

6.  Large Osteochondral Lesions of the Talus Treated With Autologous Bone Graft and Periosteum Transfer.

Authors:  Dimitrios Nikolopoulos; Neoptolemos Sergides; George Safos; Konstantinos Moustakas; Petros Safos; Andreas Moutsios-Rentzos
Journal:  Foot Ankle Orthop       Date:  2019-09-11

7.  Osteochondral Lesions of the Ankle Treated with Bone Marrow Concentrate with Hyaluronan and Fibrin: A Single-Centre Study.

Authors:  Sameera Abas; Jan Herman Kuiper; Sally Roberts; Helen McCarthy; Mike Williams; Andrew Bing; Bernhard Tins; Nilesh Makwana
Journal:  Cells       Date:  2022-02-11       Impact factor: 6.600

Review 8.  The management of talar osteochondral lesions - Current concepts.

Authors:  Tian Lan; Helen S McCarthy; Charlotte H Hulme; Karina T Wright; Nilesh Makwana
Journal:  J Arthrosc Jt Surg       Date:  2021 Jul-Sep
  8 in total

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