Literature DB >> 21892393

Primary Lumbo-sacral Spinal Epidural Non-Hodgkin's Lymphoma: A Case Report and Review of Literature.

Rahul Mally1, Mayur Sharma, Shadma Khan, Vernon Velho.   

Abstract

We present a case of 24-year-old male presented with low back pain radiating to the left lower limb, tingling numbness and weakness of 6 months duration. Magnetic resonance imaging scan with contrast reveals an extradural mass at lumbosacral region. Patient was operated with laminectomy and complete excision of the lesion was done. Patient's radicular pain relieved following the surgery and weakness also improved. Histopathology was suggestive of non-Hodgkin's lymphoma. Patient received chemotherapy which was followed by radiotherapy. Primary Non-Hodgkin's lymphoma of the lumbosacral spinal epidural tissue is an uncommon lesion. Lymphoma involves the central nervous system in 5-11% of cases either at presentation of the disease or during its course. The spinal epidural tissue is involved primarily in 0.1-3.3% of cases with spinal cord compression being the commonest presentation. Excision of the lesion followed by chemotherapy and radiotherapy is required to achieve cure.

Entities:  

Keywords:  Epidural; Lumbosacral region; Non-Hodgkin's lymphoma; Spinal

Year:  2011        PMID: 21892393      PMCID: PMC3159069          DOI: 10.4184/asj.2011.5.3.192

Source DB:  PubMed          Journal:  Asian Spine J        ISSN: 1976-1902


  7 in total

Review 1.  Spinal epidural non-Hodgkin's lymphoma: case reports of three patients presenting with spinal cord compression.

Authors:  C C Lim; B K Chong
Journal:  Singapore Med J       Date:  1996-10       Impact factor: 1.858

2.  Non-Hodgkin's lymphoma of the brain: can high dose, large volume radiation therapy improve survival? Report on a prospective trial by the Radiation Therapy Oncology Group (RTOG): RTOG 8315.

Authors:  D F Nelson; K L Martz; H Bonner; J S Nelson; J Newall; H D Kerman; J W Thomson; K J Murray
Journal:  Int J Radiat Oncol Biol Phys       Date:  1992       Impact factor: 7.038

3.  Non-Hodgkin's lymphoma presenting with spinal cord compression; a clinicopathological review of 25 cases.

Authors:  A C McDonald; J A Nicoll; R P Rampling
Journal:  Eur J Cancer       Date:  2000-01       Impact factor: 9.162

4.  Central nervous system complications by malignant lymphomas: radiation schedule and treatment results.

Authors:  K Aabo; S Walbom-Jørgensen
Journal:  Int J Radiat Oncol Biol Phys       Date:  1986-02       Impact factor: 7.038

5.  Diffuse large B-cell lymphoma in the spinal epidural space: A study of the Osaka Lymphoma Study Group.

Authors:  Naoki Wada; Masaharu Kohara; Junichiro Ikeda; Yumiko Hori; Shigeki Fujita; Masaya Okada; Hiroyasu Ogawa; Haruo Sugiyama; Shirou Fukuhara; Akihisa Kanamaru; Masayuki Hino; Yuzuru Kanakura; Eiichi Morii; Katsuyuki Aozasa
Journal:  Pathol Res Pract       Date:  2010-04-15       Impact factor: 3.250

6.  The significance of spinal cord compression as the initial manifestation of lymphoma.

Authors:  J R Perry; S S Deodhare; J M Bilbao; D Murray; P Muller
Journal:  Neurosurgery       Date:  1993-02       Impact factor: 4.654

7.  MRI of spinal epidural lymphoma.

Authors:  M Mascalchi; P Torselli; F Falaschi; G Dal Pozzo
Journal:  Neuroradiology       Date:  1995-05       Impact factor: 2.804

  7 in total
  11 in total

1.  A Rare Case of Malignant Lymphoma Occurred at Spinal Epidural Space: A Case Report.

Authors:  Hyun-Jun Cho; Jang-Bo Lee; Junseok W Hur; Sung-Won Jin; Tai-Hyoung Cho; Jung-Yul Park
Journal:  Korean J Spine       Date:  2015-09-30

Review 2.  Primary sacral non-germinal center type diffuse large B-cell lymphoma with MYC translocation: a case report and a review of the literature.

Authors:  Asami Shimada; Kei-Ji Sugimoto; Mutsumi Wakabayashi; Hidenori Imai; Yasunobu Sekiguchi; Noriko Nakamura; Tomohiro Sawada; Yasunori Ota; Norio Komatsu; Masaaki Noguchi
Journal:  Int J Clin Exp Pathol       Date:  2013-08-15

3.  Metastatic non-Hodgkin lymphoma presenting as low back pain and radiculopathy: a case report.

Authors:  Inger K Roug; Larry B McCartney
Journal:  J Chiropr Med       Date:  2012-09

Review 4.  Spinal non-Hodgkin's lymphoma mimicking a flare of disease in a patient with ankylosing spondylitis treated with anti-TNF agents: case report and review of the literature.

Authors:  Sara Monti; Nicola Boffini; Marco Lucioni; Marco Paulli; Carlomaurizio Montecucco; Roberto Caporali
Journal:  Clin Rheumatol       Date:  2014-04-05       Impact factor: 2.980

5.  MRI findings of intraspinal extradural paragonimiasis granuloma in a child.

Authors:  Yong Qin; Jinhua Cai
Journal:  Pediatr Radiol       Date:  2012-05-09

6.  A Great Mimicker in Thoracic Spine: Spinal Double Expressor Lymphoma.

Authors:  Muhammad Mufti; Khalid Nawab; Rabia Mohammad
Journal:  J Hematol (Brossard)       Date:  2018-09-01

7.  F-18 Fluorodeoxyglucose Positron Emission Tomography Computed Tomography Findings in an Interesting Case of Primary Cauda Equina Lymphoma with Literature Review.

Authors:  N C Valaiyapathy; V Saikrishna Mohan; R Ramya Priya; S Sarala; D Bhargavi; V V Ramesh Chandra; Tek Chand Kalawat
Journal:  Indian J Nucl Med       Date:  2021-12-15

8.  A Conservative Approach to the Treatment of a Rare Case of Cervical Spine Double Expressor Diffuse Large B-cell Lymphoma: A Case Report.

Authors:  Wesley Chen; Busha Hika; Caitlyn J Smith; Timothy J Parrett; Fassil B Mesfin
Journal:  Cureus       Date:  2022-01-13

9.  Primary Non-Hodgkin's Lymphoma of the Spine: A Case Report and Literature Review.

Authors:  Elias Moussaly; Bassel Nazha; Mazen Zaarour; Jean Paul Atallah
Journal:  World J Oncol       Date:  2015-10-26

10.  Primary sacral non-Hodgkin's lymphoma: report of a case and systematic review of literature.

Authors:  Satya Vijay Chigurupati; Mridula Shukla; Manoj Pandey
Journal:  World J Surg Oncol       Date:  2021-02-24       Impact factor: 2.754

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