Literature DB >> 23447899

Clinical results of topography-based customized ablations in highly aberrated eyes and keratoconus/ectasia with cross-linking.

David T C Lin1, Simon Holland, Johnson C H Tan, Gregory Moloney.   

Abstract

PURPOSE: To report results of a series of highly aberrated corneas treated with a topography-guided excimer laser ablation.
METHODS: Retrospective, nonrandomized, consecutive series of eyes treated with topography-guided photorefractive keratectomy (TG-PRK) with the customized topographical neutralization technique (TNT). Cases included postoperative refractive surgery decentered ablations, optical zone enlargement, asymmetrical astigmatism, postoperative radial keratotomy (RK), postoperative keratoplasty, keratoconus combined with collagen cross-linking (CXL), and postoperative LASIK ectasia combined with CXL. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and manifest refraction were analyzed preoperatively and 6 months postoperatively.
RESULTS: In decentered ablation cases, 94% of 37 eyes were within 1.00 diopter (D) of the attempted refractive outcome, with 76% within 0.50 D. Mean topographic, central, optical zone of uniform (monodioptric) power increased from 3.5 to 5.2 mm in 25 eyes. Thirty-one eyes treated for asymmetrical astigmatism showed improvement in cylinder from mean 1.31 to 0.52 D. Ten of 11 eyes treated for previous RK astigmatism achieved postoperative UDVA 20/40 or better. Twenty-seven eyes with postoperative keratoplasty astigmatism were treated, with 7 (25.9%) eyes gaining > or = 2 lines and 12 (44.4%) eyes gaining > or = 1 line of CDVA. Of eyes with keratoconus that were treated using TG-PRK with CXL, 42 (58%) eyes had UDVA 20/40 or better, and 66 (92%) eyes had CDVA 20/40 or better. Twelve (71%) of 17 eyes treated for postoperative LASIK ectasia using TG-PRK with CXL had UDVA 20/40 or better. Nine (53%) eyes gained > or = 2 lines of CDVA.
CONCLUSIONS: Topography-guided laser treatment with custom TNT, combined with CXL in keratoconus and ectasia, is an effective, safe, and increasingly predictable option for highly aberrated corneas.

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Year:  2012        PMID: 23447899     DOI: 10.3928/1081597X-20121005-06

Source DB:  PubMed          Journal:  J Refract Surg        ISSN: 1081-597X            Impact factor:   3.573


  19 in total

1.  [Avoidance and management of complications in laser in situ keratomileusis].

Authors:  T Kohnen; O K Klaproth
Journal:  Ophthalmologe       Date:  2013-07       Impact factor: 1.059

Review 2.  Femtosecond laser-assisted stromal keratophakia for keratoconus: A systemic review and meta-analysis.

Authors:  Andri K Riau; Hla Myint Htoon; Jorge L Alió Del Barrio; Mario Nubile; Mona El Zarif; Leonardo Mastropasqua; Jorge L Alió; Jodhbir S Mehta
Journal:  Int Ophthalmol       Date:  2021-02-20       Impact factor: 2.031

Review 3.  Corneal collagen cross-linking: a review.

Authors:  David P S O'Brart
Journal:  J Optom       Date:  2014-03-20

4.  Lens Densitometry after Corneal Cross-linking in Patients with Keratoconus Using a Scheimpflug Camera.

Authors:  Alireza Baradaran-Rafii; Mohammad Aghazazeh Amiri; Sahar Mohaghegh; Mehran Zarei-Ghanavati
Journal:  J Ophthalmic Vis Res       Date:  2015 Apr-Jun

Review 5.  Surgical Options for the Refractive Correction of Keratoconus: Myth or Reality.

Authors:  L Fernández-Vega-Cueto; V Romano; R Zaldivar; C H Gordillo; F Aiello; D Madrid-Costa; J F Alfonso
Journal:  J Ophthalmol       Date:  2017-12-18       Impact factor: 1.909

6.  High-resolution wavefront-guided surface ablation with corneal cross-linking in ectatic corneas: a pilot study.

Authors:  Gustavo E Tamayo; Claudia Castell; Pilar Vargas; Eduardo Polania; Juliana Tamayo
Journal:  Clin Ophthalmol       Date:  2017-10-03

7.  High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes.

Authors:  Gustavo E Tamayo; Claudia Castell; Pilar Vargas; Eduardo Polania; Juliana Tamayo
Journal:  Clin Ophthalmol       Date:  2020-05-12

8.  Severe long-term progressive corneal remodeling after bilateral simultaneous prophylactic crosslinking and topography-guided surface ablation with mitomycin.

Authors:  Juan Carlos Abad; Laura Martinez-Cadavid; Andrea Ocampo-Patiño; Emilio A Torrres-Netto; Renato Ambrosio
Journal:  Am J Ophthalmol Case Rep       Date:  2021-05-24

9.  One-Year Results of Simultaneous Topography-Guided Photorefractive Keratectomy and Corneal Collagen Cross-Linking in Keratoconus Utilizing a Modern Ablation Software.

Authors:  A M Sherif; M A Ammar; Y S Mostafa; S A Gamal Eldin; A A Osman
Journal:  J Ophthalmol       Date:  2015-08-23       Impact factor: 1.909

10.  Visual and Refractive Outcomes of Topography-guided Laser-assisted In Situ Keratomileusis in Virgin Eyes.

Authors:  Sharif Hashmani; Nauman Hashmani; Husna Haroon; Yusra Hashmi
Journal:  Cureus       Date:  2018-01-31
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