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Literature DB >> 23443043

MicroRNAs: a new piece in the paediatric cardiovascular disease puzzle.

Ahmed Omran¹, Dalia Elimam, Keith A Webster, Lina A Shehadeh, Fei Yin.

Abstract

Cardiovascular diseases in children comprise a large public health problem. The major goals of paediatric cardiologists and paediatric cardiovascular researchers are to identify the cause(s) of these diseases to improve treatment and preventive protocols. Recent studies show the involvement of microRNAs (miRs) in different aspects of heart development, function, and disease. Therefore, miR-based research in paediatric cardiovascular disorders is crucial for a better understanding of the underlying pathogenesis of the disease, and unravelling novel, efficient, preventive, and therapeutic means. The ultimate goal of such research is to secure normal cardiac development and hence decrease disabilities, improve clinical outcomes, and decrease the morbidity and mortality among children. This review focuses on the role of miRs in different paediatric cardiovascular conditions in an effort to encourage miR-based research in paediatric cardiovascular disorders.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：
MicroRNAs

Year: 2013 PMID： 23443043 PMCID： PMC3748175 DOI： 10.1017/S1047951113000048

Source DB: PubMed Journal: Cardiol Young ISSN： 1047-9511 Impact factor: 1.093

127 in total

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Journal: J Card Fail Date: 2010-03-03 Impact factor: 5.712

4. The incidence of asymptomatic hypertension in school children.

Authors: Cihangir Akgun; Murat Dogan; Sinan Akbayram; Oguz Tuncer; Erdal Peker; Gökmen Taskin; Sükrü Arslan; Derya Arslan
Journal: J Nippon Med Sch Date: 2010-06 Impact factor: 0.920

5. Argonaute-2-null embryonic stem cells are retarded in self-renewal and differentiation.

Authors: P Chandra Shekar; Adnan Naim; D Partha Sarathi; Satish Kumar
Journal: J Biosci Date: 2011-09 Impact factor: 1.826

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Authors: Veli K Topkara; Douglas L Mann
Journal: Per Med Date: 2010-09-01 Impact factor: 2.512

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Authors: Limei Qin; Yaosheng Chen; Yuna Niu; Weiquan Chen; Qiwei Wang; Shuqi Xiao; Anning Li; Ying Xie; Jing Li; Xiao Zhao; Zuyong He; Delin Mo
Journal: BMC Genomics Date: 2010-05-23 Impact factor: 3.969

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Authors: Huangming Xie; Lei Sun; Harvey F Lodish
Journal: Expert Opin Ther Targets Date: 2009-10 Impact factor: 6.902

Review 9. Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways.

Authors: Bernard R Wilfred; Wang-Xia Wang; Peter T Nelson
Journal: Mol Genet Metab Date: 2007-05-22 Impact factor: 4.797

10. Adolescent overweight and future adult coronary heart disease.

Authors: Kirsten Bibbins-Domingo; Pamela Coxson; Mark J Pletcher; James Lightwood; Lee Goldman
Journal: N Engl J Med Date: 2007-12-06 Impact factor: 91.245

12 in total

1. Changes in microglial inflammation-related and brain-enriched MicroRNAs expressions in response to in vitro oxygen-glucose deprivation.

Authors: Huimin Kong; Ahmed Omran; Muhammad Usman Ashhab; Na Gan; Jing Peng; Fang He; Liwen Wu; Xiaolu Deng; Fei Yin
Journal: Neurochem Res Date: 2013-12-12 Impact factor: 3.996

2. Urinary Excretion of MicroRNA-126 Is a Biomarker for Hemangioma Proliferation.

Authors: Ayan Biswas; Xueliang Pan; Melissa Meyer; Savita Khanna; Sashwati Roy; Gregory Pearson; Richard Kirschner; Patricia Witman; Esteban Fernandez Faith; Chandan K Sen; Gayle M Gordillo
Journal: Plast Reconstr Surg Date: 2017-06 Impact factor: 4.730

3. Evaluation of epigenetic alterations (mir-126 and mir-155 expression levels) in Mexican children exposed to inorganic arsenic via drinking water.

Authors: Mónica S Pérez-Vázquez; Ángeles C Ochoa-Martínez; Tania RuÍz-Vera; Yesenia Araiza-Gamboa; Iván N Pérez-Maldonado
Journal: Environ Sci Pollut Res Int Date: 2017-10-06 Impact factor: 4.223

4. Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy.

Authors: Muhammad Usman Ashhab; Ahmed Omran; Huimin Kong; Na Gan; Fang He; Jing Peng; Fei Yin
Journal: J Mol Neurosci Date: 2013-05-01 Impact factor: 3.444

Review 5. The roles of epicardial adipose tissue in heart failure.

Authors: Ying Song; Fei Song; Chan Wu; Yi-Xiang Hong; Gang Li
Journal: Heart Fail Rev Date: 2022-01 Impact factor: 4.214

6. Effects of MRP8, LPS, and lenalidomide on the expressions of TNF-α , brain-enriched, and inflammation-related microRNAs in the primary astrocyte culture.

Authors: Ahmed Omran; Muhammad Usman Ashhab; Na Gan; Huimin Kong; Jing Peng; Fei Yin
Journal: ScientificWorldJournal Date: 2013-09-21