Michael Lettau1, Mona Laible. 1. Division of Neuroradiology, Department of Neurosurgery, University of Freiburg Medical Center, Breisacher Str. 64, 79106 Freiburg, Germany. michael_lettau@gmx.de
Abstract
BACKGROUND AND PURPOSE: In patients with hyperacute ischemic stroke, early demonstration of infarction is essential. Diffusion weighted imaging (DWI) is the key method for detecting hyperacute infarction. The value of high b-value DWI in hyperacute ischemic stroke is controversial at 1.5 T, and is unknown at 3 T. The aim of this study is to explore the value of high b-value versus standard b-value DWI at 3T in hyperacute stroke with quantitative and qualitative analysis. MATERIAL AND METHODS: This study prospectively included 104 consecutive patients with hyperacute stroke. At 3 T, conventional MR sequences and DWI were performed. The examination included a standard DWI (b = 1000 s/mm(2)) and two high b-value DWI (b = 3000 s/mm(2) and b = 5000 s/mm(2)). Qualitative and quantitative analysis was performed. RESULTS: With increasing b value, DW images appeared noisier. The number of detected lesions was significantly higher on b = 3000 images than on the other DW images and higher on b = 5000 images than on b = 1000 images. The number of lesions greater than 1 cm was not significantly different. Lesion conspicuity was higher, boundary better seen, lesion extent bigger, and estimation of final infarct size was better on high b-value than on standard b-value DWI. Contrast-to-noise-ratio (CNR) and signal-to-noise-ratio (SNR) decreased and contrast ratio (CR) increased on high b-value DWI compared to standard b-value DWI. CONCLUSION: At 3 T, high b-value DWI was superior to standard b-value DWI in detection of hyperacute infarction and prediction of final infarct size in spite of increasing imaging artifacts.
BACKGROUND AND PURPOSE: In patients with hyperacute ischemic stroke, early demonstration of infarction is essential. Diffusion weighted imaging (DWI) is the key method for detecting hyperacute infarction. The value of high b-value DWI in hyperacute ischemic stroke is controversial at 1.5 T, and is unknown at 3 T. The aim of this study is to explore the value of high b-value versus standard b-value DWI at 3T in hyperacute stroke with quantitative and qualitative analysis. MATERIAL AND METHODS: This study prospectively included 104 consecutive patients with hyperacute stroke. At 3 T, conventional MR sequences and DWI were performed. The examination included a standard DWI (b = 1000 s/mm(2)) and two high b-value DWI (b = 3000 s/mm(2) and b = 5000 s/mm(2)). Qualitative and quantitative analysis was performed. RESULTS: With increasing b value, DW images appeared noisier. The number of detected lesions was significantly higher on b = 3000 images than on the other DW images and higher on b = 5000 images than on b = 1000 images. The number of lesions greater than 1 cm was not significantly different. Lesion conspicuity was higher, boundary better seen, lesion extent bigger, and estimation of final infarct size was better on high b-value than on standard b-value DWI. Contrast-to-noise-ratio (CNR) and signal-to-noise-ratio (SNR) decreased and contrast ratio (CR) increased on high b-value DWI compared to standard b-value DWI. CONCLUSION: At 3 T, high b-value DWI was superior to standard b-value DWI in detection of hyperacute infarction and prediction of final infarct size in spite of increasing imaging artifacts.
Authors: Thomas Sartoretti; Elisabeth Sartoretti; Michael Wyss; Manoj Mannil; Luuk van Smoorenburg; Barbara Eichenberger; Carolin Reischauer; Alex Alfieri; Christoph Binkert; Sabine Sartoretti-Schefer Journal: Br J Radiol Date: 2021-02-17 Impact factor: 3.039
Authors: Annemieke Ter Telgte; Kim Wiegertjes; Benno Gesierich; José P Marques; Mathias Huebner; Jabke J de Klerk; Floris H B M Schreuder; Miguel A Araque Caballero; Hugo J Kuijf; David G Norris; Catharina J M Klijn; Martin Dichgans; Anil M Tuladhar; Marco Duering; Frank-Erik de Leeuw Journal: Ann Neurol Date: 2019-08-12 Impact factor: 10.422