Literature DB >> 23429393

(18)F-FDG PET/CT in differentiating acute tuberculous from idiopathic pericarditis: preliminary study.

Aisheng Dong1, Hui Dong, Yang Wang, Chao Cheng, Changjing Zuo, Jianping Lu.   

Abstract

PURPOSE: The aim of this study was to evaluate retrospectively the diagnostic capability of F-FDG PET/CT in differentiating acute tuberculous from idiopathic pericarditis.
METHODS: FDG PET/CT findings were reviewed in 15 patients with acute tuberculous (n = 5) or idiopathic pericarditis (n = 10). The maximal thickness and SUVmax of the pericardium and the number, size, and SUVmax of the mediastinal and supraclavicular lymph nodes with increased FDG uptake were measured.
RESULTS: All patients had small-to-large amount of pericardial effusion. The patients with acute tuberculous pericarditis (n = 5) showed diffuse (n = 3) or multifocal (n = 2) FDG uptake in the pericardia. The patients with acute idiopathic pericarditis (n = 10) showed diffuse (n = 6) or regional (n = 4) FDG uptake in the pericardia. The mean (SD) pericardial thickness and SUVmax of acute tuberculous pericarditis were significantly higher than those of acute idiopathic pericarditis (5.1 [1.0] vs 3.4 [0.9], P < 0.05; 13.5 [3.9] vs 3.0 [0.7], P < 0.05, respectively). A total of 69 mediastinal and supraclavicular lymph nodes with increased FDG uptake were observed in all 15 patients (44 in patients with acute tuberculous pericarditis and 25 in patients with acute idiopathic pericarditis). The mean (SD) SUVmax of mediastinal and supraclavicular lymph nodes of acute tuberculous pericarditis (5.3 [1.8]) was significantly higher than that of acute idiopathic pericarditis (2.8 [0.6], P < 0.05). There was no significant difference in the mean size of the mediastinal and supraclavicular lymph nodes between acute tuberculous and idiopathic pericarditis.
CONCLUSIONS: The degrees of FDG uptake in the pericardium and the mediastinal and supraclavicular lymph nodes are useful for differentiating acute tuberculous from idiopathic pericarditis. Familiarity with the FDG uptake patterns of acute tuberculous and idiopathic pericarditis may be helpful for successful (especially timely) diagnosis and treatment.

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Year:  2013        PMID: 23429393     DOI: 10.1097/RLU.0b013e31827a2537

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


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Review 9.  Tuberculous Pericarditis-Own Experiences and Recent Recommendations.

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  9 in total

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