Literature DB >> 23422915

Liposomal amphotericin B displays rapid dose-dependent activity against Candida albicans biofilms.

Gordon Ramage1, Anto Jose, Leighann Sherry, David F Lappin, Brian Jones, Craig Williams.   

Abstract

Biofilms formed by Candida albicans bloodstream isolates on catheters are an important clinical problem. Devising chemotherapeutic strategies to treat these in situ is an attractive option. We report here that liposomal amphotericin effectively kills C. albicans biofilms rapidly (12 h) and effectively (>90%) in a dose-dependent manner, whereas caspofungin displays an inverse concentration-dependent effect. This study has implications for considering the effective doses of antifungal agents used for catheter lock therapy.

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Year:  2013        PMID: 23422915      PMCID: PMC3632906          DOI: 10.1128/AAC.02344-12

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  19 in total

1.  Should lock therapy always be avoided for central venous catheter-associated fungal bloodstream infections?

Authors:  P Viale; N Petrosillo; L Signorini; M Puoti; G Carosi
Journal:  Clin Infect Dis       Date:  2001-12-01       Impact factor: 9.079

2.  Antibiotic-lock therapy and erythromycin for treatment of catheter-related Candida parapsilosis and Staphylococcus aureus infections.

Authors:  Chao-Yi Wu; Ping-Ing Lee
Journal:  J Antimicrob Chemother       Date:  2007-07-10       Impact factor: 5.790

3.  Guidelines for the prevention of intravascular catheter-related infections.

Authors:  Naomi P O'Grady; Mary Alexander; Lillian A Burns; E Patchen Dellinger; Jeffrey Garland; Stephen O Heard; Pamela A Lipsett; Henry Masur; Leonard A Mermel; Michele L Pearson; Issam I Raad; Adrienne G Randolph; Mark E Rupp; Sanjay Saint
Journal:  Clin Infect Dis       Date:  2011-04-01       Impact factor: 9.079

4.  Liposomal amphotericin B eradicates Candida albicans biofilm in a continuous catheter flow model.

Authors:  Marc Seidler; Stefanie Salvenmoser; Frank-Michael C Müller
Journal:  FEMS Yeast Res       Date:  2010-03-05       Impact factor: 2.796

5.  Could liposomal amphotericin B (L-AMB) lock solutions be useful to inhibit Candida spp. biofilms on silicone biomaterials?

Authors:  Delphine Toulet; Cécile Debarre; Christine Imbert
Journal:  J Antimicrob Chemother       Date:  2011-11-11       Impact factor: 5.790

6.  Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms.

Authors:  G Ramage; K Vande Walle; B L Wickes; J L López-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2001-09       Impact factor: 5.191

7.  Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins.

Authors:  D M Kuhn; T George; J Chandra; P K Mukherjee; M A Ghannoum
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

8.  Paradoxical growth effect of caspofungin observed on biofilms and planktonic cells of five different Candida species.

Authors:  Analy S Melo; Arnaldo L Colombo; Beth A Arthington-Skaggs
Journal:  Antimicrob Agents Chemother       Date:  2007-06-25       Impact factor: 5.191

9.  Elevated chitin content reduces the susceptibility of Candida species to caspofungin.

Authors:  Louise A Walker; Neil A R Gow; Carol A Munro
Journal:  Antimicrob Agents Chemother       Date:  2012-10-22       Impact factor: 5.191

10.  Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital.

Authors:  Mario Tumbarello; Barbara Fiori; Enrico Maria Trecarichi; Patrizia Posteraro; Angela Raffaella Losito; Alessio De Luca; Maurizio Sanguinetti; Giovanni Fadda; Roberto Cauda; Brunella Posteraro
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

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  14 in total

1.  Local delivery polymer provides sustained antifungal activity of amphotericin B with reduced cytotoxicity.

Authors:  Rebecca M Haley; Sean T Zuckerman; Catherine A Gormley; Julius N Korley; Horst A von Recum
Journal:  Exp Biol Med (Maywood)       Date:  2019-03-21

2.  In Vitro Antibiofilm Activity of Eucarobustol E against Candida albicans.

Authors:  Rui-Huan Liu; Zhi-Chun Shang; Tian-Xiao Li; Ming-Hua Yang; Ling-Yi Kong
Journal:  Antimicrob Agents Chemother       Date:  2017-07-25       Impact factor: 5.191

Review 3.  Antimicrobial lock therapy in central-line associated bloodstream infections: a systematic review.

Authors:  Matteo Vassallo; Brigitte Dunais; Pierre-Marie Roger
Journal:  Infection       Date:  2015-02-06       Impact factor: 3.553

4.  Candida albicans biofilm development on medically-relevant foreign bodies in a mouse subcutaneous model followed by bioluminescence imaging.

Authors:  Soňa Kucharíková; Greetje Vande Velde; Uwe Himmelreich; Patrick Van Dijck
Journal:  J Vis Exp       Date:  2015-01-27       Impact factor: 1.355

5.  Biofilm Production and Antibiofilm Activity of Echinocandins and Liposomal Amphotericin B in Echinocandin-Resistant Yeast Species.

Authors:  Laura Judith Marcos-Zambrano; Marta Gómez-Perosanz; Pilar Escribano; Oscar Zaragoza; Emilio Bouza; Jesús Guinea
Journal:  Antimicrob Agents Chemother       Date:  2016-05-23       Impact factor: 5.191

6.  In vitro determination of the efficacy of scorpion venoms as anti-cancer agents against colorectal cancer cells: a nano-liposomal delivery approach.

Authors:  Abdulrahman K Al-Asmari; Zabih Ullah; Ali Al Balowi; Mozaffarul Islam
Journal:  Int J Nanomedicine       Date:  2017-01-13

7.  Risk assessment for the spread of Candida sp. in dental chair unit waterlines using molecular techniques.

Authors:  Wissame Mazari; Zahia Boucherit-Otmani; Imad Abdelhamid El Haci; Amine Ilahi; Kebir Boucherit
Journal:  Int Dent J       Date:  2018-05-04       Impact factor: 2.607

8.  Candida albicans Fungaemia following Traumatic Urethral Catheterisation in a Paraplegic Patient with Diabetes Mellitus and Candiduria Treated by Caspofungin.

Authors:  Subramanian Vaidyanathan; Bakul Soni; Peter Hughes; Gordon Ramage; Leighann Sherry; Gurpreet Singh; Paul Mansour
Journal:  Case Rep Infect Dis       Date:  2013-10-08

Review 9.  Recent insights into Candida albicans biofilm resistance mechanisms.

Authors:  Lotte Mathé; Patrick Van Dijck
Journal:  Curr Genet       Date:  2013-08-25       Impact factor: 3.886

Review 10.  Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?

Authors:  Aline Raquel Voltan; Guillermo Quindós; Kaila P Medina Alarcón; Ana Marisa Fusco-Almeida; Maria José Soares Mendes-Giannini; Marlus Chorilli
Journal:  Int J Nanomedicine       Date:  2016-08-08
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