Literature DB >> 23422555

Drug discovery: Diversifying complexity.

Indrajeet Sharma, Derek S Tan.   

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Year:  2013        PMID： 23422555     DOI： 10.1038/nchem.1581

Source DB:  PubMed          Journal:  Nat Chem        ISSN： 1755-4330            Impact factor:   24.427


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  16 in total

Review 1.  Natural products as sources of new drugs over the 30 years from 1981 to 2010.

Authors:  David J Newman; Gordon M Cragg
Journal:  J Nat Prod       Date:  2012-02-08       Impact factor: 4.050

Review 2.  Cellular targets of natural products.

Authors:  Neil Dixon; Lu Shin Wong; Torsten H Geerlings; Jason Micklefield
Journal:  Nat Prod Rep       Date:  2007-10-17       Impact factor: 13.423

Review 3.  The impact of aromatic ring count on compound developability--are too many aromatic rings a liability in drug design?

Authors:  Timothy J Ritchie; Simon J F Macdonald
Journal:  Drug Discov Today       Date:  2009-09-01       Impact factor: 7.851

4.  Strategies to improve in vivo toxicology outcomes for basic candidate drug molecules.

Authors:  Tim Luker; Lilian Alcaraz; Kamaldeep K Chohan; Niklas Blomberg; Dearg S Brown; Roger J Butlin; Thomas Elebring; Andrew M Griffin; Simon Guile; Stephen St-Gallay; Britt-Marie Swahn; Steve Swallow; Michael J Waring; Mark C Wenlock; Paul D Leeson
Journal:  Bioorg Med Chem Lett       Date:  2011-07-27       Impact factor: 2.823

Review 5.  Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective.

Authors:  Renato A Bauer; Jacqueline M Wurst; Derek S Tan
Journal:  Curr Opin Chem Biol       Date:  2010-03-02       Impact factor: 8.822

Review 6.  Privileged scaffolds for library design and drug discovery.

Authors:  Matthew E Welsch; Scott A Snyder; Brent R Stockwell
Journal:  Curr Opin Chem Biol       Date:  2010-03-18       Impact factor: 8.822

Review 7.  Interfacial inhibitors: targeting macromolecular complexes.

Authors:  Yves Pommier; Christophe Marchand
Journal:  Nat Rev Drug Discov       Date:  2011-12-16       Impact factor: 84.694

8.  Escape from flatland: increasing saturation as an approach to improving clinical success.

Authors:  Frank Lovering; Jack Bikker; Christine Humblet
Journal:  J Med Chem       Date:  2009-11-12       Impact factor: 7.446

9.  Quantifying biogenic bias in screening libraries.

Authors:  Jérôme Hert; John J Irwin; Christian Laggner; Michael J Keiser; Brian K Shoichet
Journal:  Nat Chem Biol       Date:  2009-05-31       Impact factor: 15.040

Review 10.  Towards the optimal screening collection: a synthesis strategy.

Authors:  Thomas E Nielsen; Stuart L Schreiber
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336
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  4 in total

1.  Atropisomeric [(diphosphine)Au2 Cl2 ] complexes and their catalytic activity towards asymmetric cycloisomerisation of 1,6-enynes.

Authors:  Elena M Barreiro; Ekaterina V Boltukhina; Andrew J P White; King Kuok Mimi Hii
Journal:  Chemistry       Date:  2014-12-11       Impact factor: 5.236

2.  A [3 + 2] cycloaddition/C-arylation of isatin N,N'-cyclic azomethine imine 1,3-dipole with arynes.

Authors:  Qiaomei Jin; Dongjian Zhang; Jian Zhang
Journal:  RSC Adv       Date:  2020-08-19       Impact factor: 4.036

Review 3.  Catalytic enantioselective construction of vicinal quaternary carbon stereocenters.

Authors:  Feng Zhou; Lei Zhu; Bo-Wen Pan; Yang Shi; Yun-Lin Liu; Jian Zhou
Journal:  Chem Sci       Date:  2020-07-28       Impact factor: 9.825

4.  Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones.

Authors:  Peng-Wei Xu; Jia-Kuan Liu; Lan Shen; Zhong-Yan Cao; Xiao-Li Zhao; Jun Yan; Jian Zhou
Journal:  Nat Commun       Date:  2017-11-20       Impact factor: 14.919
  4 in total

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