Literature DB >> 23419903

Diabetes: Looking back at Look AHEAD--giving lifestyle a chance.

Jean-Pierre Després, Paul Poirier.   

Abstract

The Look AHEAD trial did not show that a lifestyle modification programme aimed at weight loss could reduce the incidence of cardiovascular disease events. We attempt to address why this trial was 'negative', and emphasize that further randomized trials of lifestyle modification focusing on the effects of physical activity and exercise are needed.

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Mesh：

Year:  2013        PMID： 23419903     DOI： 10.1038/nrcardio.2013.16

Source DB:  PubMed          Journal:  Nat Rev Cardiol        ISSN： 1759-5002            Impact factor:   32.419


  9 in total

1.  Achieving cardiovascular health: a bleak outlook or tremendous potential?

Authors:  Dariush Mozaffarian
Journal:  J Am Coll Cardiol       Date:  2011-04-19       Impact factor: 24.094

2.  Rethinking our approach to physical activity.

Authors:  Pamela Das; Richard Horton
Journal:  Lancet       Date:  2012-07-21       Impact factor: 79.321

3.  Midcourse correction to a clinical trial when the event rate is underestimated: the Look AHEAD (Action for Health in Diabetes) Study.

Authors:  Frederick L Brancati; Mary Evans; Curt D Furberg; Nancy Geller; Steven Haffner; Steven E Kahn; Peter G Kaufmann; Cora E Lewis; David M Nathan; Bertram Pitt; Monika M Safford
Journal:  Clin Trials       Date:  2012-02       Impact factor: 2.486

4.  Four-year weight losses in the Look AHEAD study: factors associated with long-term success.

Authors:  Thomas A Wadden; Rebecca H Neiberg; Rena R Wing; Jeanne M Clark; Linda M Delahanty; James O Hill; Jonathan Krakoff; Amy Otto; Donna H Ryan; Mara Z Vitolins
Journal:  Obesity (Silver Spring)       Date:  2011-07-21       Impact factor: 5.002

Review 5.  Lipid homeostasis, lipotoxicity and the metabolic syndrome.

Authors:  Roger H Unger; Gregory O Clark; Philipp E Scherer; Lelio Orci
Journal:  Biochim Biophys Acta       Date:  2009-11-27

6.  Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes.

Authors:  Donna H Ryan; Mark A Espeland; Gary D Foster; Steven M Haffner; Van S Hubbard; Karen C Johnson; Steven E Kahn; William C Knowler; Susan Z Yanovski
Journal:  Control Clin Trials       Date:  2003-10

7.  Association of an intensive lifestyle intervention with remission of type 2 diabetes.

Authors:  Edward W Gregg; Haiying Chen; Lynne E Wagenknecht; Jeanne M Clark; Linda M Delahanty; John Bantle; Henry J Pownall; Karen C Johnson; Monika M Safford; Abbas E Kitabchi; F Xavier Pi-Sunyer; Rena R Wing; Alain G Bertoni
Journal:  JAMA       Date:  2012-12-19       Impact factor: 56.272

8.  Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial.

Authors:  Xavier Pi-Sunyer; George Blackburn; Frederick L Brancati; George A Bray; Renee Bright; Jeanne M Clark; Jeffrey M Curtis; Mark A Espeland; John P Foreyt; Kathryn Graves; Steven M Haffner; Barbara Harrison; James O Hill; Edward S Horton; John Jakicic; Robert W Jeffery; Karen C Johnson; Steven Kahn; David E Kelley; Abbas E Kitabchi; William C Knowler; Cora E Lewis; Barbara J Maschak-Carey; Brenda Montgomery; David M Nathan; Jennifer Patricio; Anne Peters; J Bruce Redmon; Rebecca S Reeves; Donna H Ryan; Monika Safford; Brent Van Dorsten; Thomas A Wadden; Lynne Wagenknecht; Jacqueline Wesche-Thobaben; Rena R Wing; Susan Z Yanovski
Journal:  Diabetes Care       Date:  2007-03-15       Impact factor: 19.112

Review 9.  Nonpharmacologic therapy and exercise in the prevention of type 2 diabetes.

Authors:  Jaakko Tuomilehto
Journal:  Diabetes Care       Date:  2009-11       Impact factor: 19.112
  9 in total
  11 in total

Review 1.  Role of bariatric surgery in diabetes.

Authors:  Paul Poirier; Audrey Auclair
Journal:  Curr Cardiol Rep       Date:  2014-02       Impact factor: 2.931

Review 2.  Look inside Look AHEAD: why the glass is more than half-full.

Authors:  Helmut Steinberg; Crystal Jacovino; Abbas E Kitabchi
Journal:  Curr Diab Rep       Date:  2014-07       Impact factor: 4.810

3.  Enhanced motivational interviewing for reducing weight and increasing physical activity in adults with high cardiovascular risk: the MOVE IT three-arm RCT.

Authors:  Khalida Ismail; Daniel Stahl; Adam Bayley; Katherine Twist; Kurtis Stewart; Katie Ridge; Emma Britneff; Mark Ashworth; Nicole de Zoysa; Jennifer Rundle; Derek Cook; Peter Whincup; Janet Treasure; Paul McCrone; Anne Greenough; Kirsty Winkley
Journal:  Health Technol Assess       Date:  2019-12       Impact factor: 4.014

4.  Diabetes: Look AHEAD published: weight loss not linked to fewer cardiovascular events in patients with type 2 diabetes.

Authors:  Bryony M Mearns
Journal:  Nat Rev Endocrinol       Date:  2013-07-09       Impact factor: 43.330

5.  Diabetes: Look AHEAD published: weight loss not linked to fewer cardiovascular events in patients with type 2 diabetes.

Authors:  Bryony M Mearns
Journal:  Nat Rev Cardiol       Date:  2013-07-09       Impact factor: 32.419

6.  Effect of a Weight Loss and Lifestyle Intervention on Dietary Behavior in Men with Obstructive Sleep Apnea: The INTERAPNEA Trial.

Authors:  Almudena Carneiro-Barrera; Francisco J Amaro-Gahete; Lucas Jurado-Fasoli; Germán Sáez-Roca; Carlos Martín-Carrasco; Francisco J Tinahones; Jonatan R Ruiz
Journal:  Nutrients       Date:  2022-06-30       Impact factor: 6.706

7.  Intensive lifestyle intervention reduces urinary incontinence in overweight/obese men with type 2 diabetes: results from the Look AHEAD trial.

Authors:  Benjamin N Breyer; Suzanne Phelan; Patricia E Hogan; Raymond C Rosen; Abbas E Kitabchi; Rena R Wing; Jeanette S Brown
Journal:  J Urol       Date:  2014-02-14       Impact factor: 7.450

8.  Association of Comorbid and Metabolic Factors with Optimal Control of Type 2 Diabetes Mellitus.

Authors:  Satyajeet Roy; Anthony Sherman; Mary Joan Monari-Sparks; Olga Schweiker; Navjot Jain; Etty Sims; Michelle Breda; Gita P Byraiah; Ryan George Belecanech; Michael Domenic Coletta; Cristian Javier Barrios; Krystal Hunter; John P Gaughan
Journal:  N Am J Med Sci       Date:  2016-01

Review 9.  Behaviour change techniques targeting both diet and physical activity in type 2 diabetes: A systematic review and meta-analysis.

Authors:  Kevin A Cradock; Gearóid ÓLaighin; Francis M Finucane; Heather L Gainforth; Leo R Quinlan; Kathleen A Martin Ginis
Journal:  Int J Behav Nutr Phys Act       Date:  2017-02-08       Impact factor: 6.457

Review 10.  Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk.

Authors:  Devon A Dobrosielski; Christopher Papandreou; Susheel P Patil; Jordi Salas-Salvadó
Journal:  Eur Respir Rev       Date:  2017-06-28
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