OBJECTIVE: To evaluate the new DXA VAT method on an Asian Chinese population by comparing to a reference method, computed tomography (CT). DESIGN AND METHODS: In total, 145 adult men and women volunteers, representing a wide range of ages (19-83 years) and BMI values (18.5-39.3 kg/m(2) ) were studied with both DXA and CT. RESULTS: The coefficient of determination (r(2) ) for regression of CT on DXA values was 0.947 for females, 0.891 for males and 0.915 combined. The 95% confidence interval for r was 0.940-0.969 for the combined data. The Bland-Altman test showed a VAT bias (CT as standard method) of 143 cm(3) for females and 379 cm(3) for males. Combined, the bias was 262 cm(3) with 95% limits of agreement of -232 to 755 cm(3) . While the current DXA method moderately overestimates the VAT volume for the study subjects, a further analysis suggested that the overestimation could be largely contributed to VAT movement due to breath-holding status. CONCLUSIONS: For Asian Chinese, VAT measured with DXA is highly correlated to VAT measured with CT. Validation of the DXA VAT tool using a reference method (e.g., CT) needs to carefully control the breath-holding protocol.
OBJECTIVE: To evaluate the new DXA VAT method on an Asian Chinese population by comparing to a reference method, computed tomography (CT). DESIGN AND METHODS: In total, 145 adult men and women volunteers, representing a wide range of ages (19-83 years) and BMI values (18.5-39.3 kg/m(2) ) were studied with both DXA and CT. RESULTS: The coefficient of determination (r(2) ) for regression of CT on DXA values was 0.947 for females, 0.891 for males and 0.915 combined. The 95% confidence interval for r was 0.940-0.969 for the combined data. The Bland-Altman test showed a VAT bias (CT as standard method) of 143 cm(3) for females and 379 cm(3) for males. Combined, the bias was 262 cm(3) with 95% limits of agreement of -232 to 755 cm(3) . While the current DXA method moderately overestimates the VAT volume for the study subjects, a further analysis suggested that the overestimation could be largely contributed to VAT movement due to breath-holding status. CONCLUSIONS: For Asian Chinese, VAT measured with DXA is highly correlated to VAT measured with CT. Validation of the DXA VAT tool using a reference method (e.g., CT) needs to carefully control the breath-holding protocol.
Authors: John T Schousboe; Lisa Langsetmo; Ann V Schwartz; Brent C Taylor; Tien N Vo; Allyson M Kats; Elizabeth Barrett-Connor; Eric S Orwoll; Lynn M Marshall; Iva Miljkovic; Nancy E Lane; Kristine E Ensrud Journal: J Clin Densitom Date: 2017-02-24 Impact factor: 2.617
Authors: Martin Reinhardt; Paolo Piaggi; Barbara DeMers; Cathy Trinidad; Jonathan Krakoff Journal: Obesity (Silver Spring) Date: 2016-12-21 Impact factor: 5.002
Authors: A Mohammad; E De Lucia Rolfe; A Sleigh; T Kivisild; K Behbehani; N J Wareham; S Brage; T Mohammad Journal: Nutr Diabetes Date: 2017-01-09 Impact factor: 5.097
Authors: Radhika V Seimon; Anthony L Wild-Taylor; Alice A Gibson; Claudia Harper; Sally McClintock; Hamish A Fernando; Michelle S H Hsu; Felipe Q da Luz; Shelley E Keating; Nathan A Johnson; Stuart M Grieve; Tania P Markovic; Ian D Caterson; Nuala M Byrne; Amanda Sainsbury Journal: Nutrients Date: 2018-02-20 Impact factor: 5.717
Authors: John T Schousboe; Allyson M Kats; Lisa Langsetmo; Tien N Vo; Brent C Taylor; Ann V Schwartz; Peggy M Cawthon; Cora E Lewis; Elizabeth Barrett-Connor; Andrew R Hoffman; Eric S Orwoll; Kristine E Ensrud Journal: J Am Heart Assoc Date: 2018-08-21 Impact factor: 5.501