OBJECTIVE: To evaluate the precision of the iDXA for total body composition and fat distribution measurements in severely obese patients. DESIGN AND METHODS: Sixty-five severely obese participants with a mean age of 46 ± 11 years, BMI of 49 ± 6 kg/m(2) , and a mean body mass of 137.3 ± 20.9 kg took part in this investigation. Two consecutive iDXA scans with repositioning of the total body were conducted for each participant. The coefficient of variation (CV), the root-mean-square (RMS) averages of standard deviations of repeated measurements, the corresponding 95% least significant change, and Intraclass Correlations (ICC) were calculated. RESULTS: Precision expressed as % CV, for total body bone mineral content, fat free mass, total body fat, total body lean, and % total body fat were 1.08%, 0.94%, 0.90%, 1.00%, 0.79%, respectively. Precision was 1.44% for gynoid fat distribution and 1.64% for android fat (AF) distribution. The ICCs in all DXA measurements were 0.99 with % AF having the lowest at 0.96. CONCLUSIONS: The GE Lunar iDXA™ demonstrated excellent precision for total body composition assessments and is the first study to assess reproducibility in severely obese individuals.
OBJECTIVE: To evaluate the precision of the iDXA for total body composition and fat distribution measurements in severely obesepatients. DESIGN AND METHODS: Sixty-five severely obeseparticipants with a mean age of 46 ± 11 years, BMI of 49 ± 6 kg/m(2) , and a mean body mass of 137.3 ± 20.9 kg took part in this investigation. Two consecutive iDXA scans with repositioning of the total body were conducted for each participant. The coefficient of variation (CV), the root-mean-square (RMS) averages of standard deviations of repeated measurements, the corresponding 95% least significant change, and Intraclass Correlations (ICC) were calculated. RESULTS: Precision expressed as % CV, for total body bone mineral content, fat free mass, total body fat, total body lean, and % total body fat were 1.08%, 0.94%, 0.90%, 1.00%, 0.79%, respectively. Precision was 1.44% for gynoid fat distribution and 1.64% for android fat (AF) distribution. The ICCs in all DXA measurements were 0.99 with % AF having the lowest at 0.96. CONCLUSIONS: The GE Lunar iDXA™ demonstrated excellent precision for total body composition assessments and is the first study to assess reproducibility in severely obese individuals.
Authors: Shannon A Morrison; Robert M Petri; Heather L Hunter; Dheeraj Raju; Barbara Gower Journal: J Clin Densitom Date: 2015-07-21 Impact factor: 2.617
Authors: Fanny Buckinx; Francesco Landi; Matteo Cesari; Roger A Fielding; Marjolein Visser; Klaus Engelke; Stefania Maggi; Elaine Dennison; Nasser M Al-Daghri; Sophie Allepaerts; Jurgen Bauer; Ivan Bautmans; Maria Luisa Brandi; Olivier Bruyère; Tommy Cederholm; Francesca Cerreta; Antonio Cherubini; Cyrus Cooper; Alphonso Cruz-Jentoft; Eugene McCloskey; Bess Dawson-Hughes; Jean-Marc Kaufman; Andrea Laslop; Jean Petermans; Jean-Yves Reginster; René Rizzoli; Sian Robinson; Yves Rolland; Ricardo Rueda; Bruno Vellas; John A Kanis Journal: J Cachexia Sarcopenia Muscle Date: 2018-01-19 Impact factor: 12.910
Authors: Brian C Clark; Dallin Tavoian; Bret H Goodpaster; Peggy M Cawthon; Ross D Hansen; Todd M Manini Journal: J Cachexia Sarcopenia Muscle Date: 2019-01-24 Impact factor: 12.910