Literature DB >> 23417835

Non-viral gene delivery via membrane-penetrating, mannose-targeting supramolecular self-assembled nanocomplexes.

Lichen Yin1, Ziyuan Song, Kyung Hoon Kim, Nan Zheng, Nathan P Gabrielson, Jianjun Cheng.   

Abstract

Supramolecular self-assembled nanocomplexes (SSANs) capable of mannose receptor-mediated endocytosis and permeable to cellular and endosomal membranes are developed via the assembly of multiple rationally designed, function-specific materials. As a unique non-viral gene delivery vector, SSANs outperform commercial transfection reagents, including LPF2000, PEI, and jetPEI, by up to 2 orders of magnitude.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23417835      PMCID： PMC3757134          DOI： 10.1002/adma.201205088

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  43 in total

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Journal:  ACS Nano       Date:  2010-10-26       Impact factor: 15.881

2.  Optically triggered release of DNA from multivalent dendrons by degrading and charge-switching multivalency.

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Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

3.  Virion-mimicking nanocapsules from pH-controlled hierarchical self-assembly for gene delivery.

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Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  The effect of particle design on cellular internalization pathways.

Authors:  Stephanie E A Gratton; Patricia A Ropp; Patrick D Pohlhaus; J Christopher Luft; Victoria J Madden; Mary E Napier; Joseph M DeSimone
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-12       Impact factor: 11.205

5.  Interactions of oleic acid and model stratum corneum membranes as seen by 2H NMR.

Authors:  Amy C Rowat; Neil Kitson; Jenifer L Thewalt
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6.  Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol.

Authors:  K von Figura; V Gieselmann; A Hasilik
Journal:  Biochem J       Date:  1985-01-15       Impact factor: 3.857

7.  Before and after endosomal escape: roles of stimuli-converting siRNA/polymer interactions in determining gene silencing efficiency.

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8.  Application of an HIV gp41-derived peptide for enhanced intracellular trafficking of synthetic gene and siRNA delivery vehicles.

Authors:  Ester J Kwon; Jamie M Bergen; Suzie H Pun
Journal:  Bioconjug Chem       Date:  2008-04-01       Impact factor: 4.774

9.  Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles.

Authors:  Fan Yang; Seung-Woo Cho; Sun Mi Son; Said R Bogatyrev; Deepika Singh; Jordan J Green; Ying Mei; Sohyun Park; Suk Ho Bhang; Byung-Soo Kim; Robert Langer; Daniel G Anderson
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10.  Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins.

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  23 in total

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Journal:  Biomaterials       Date:  2014-03-24       Impact factor: 12.479

Review 2.  Ionic α-helical polypeptides toward nonviral gene delivery.

Authors:  Rujing Zhang; Ziyuan Song; Lichen Yin; Nan Zheng; Haoyu Tang; Hua Lu; Nathan P Gabrielson; Yao Lin; Kyung Kim; Jianjun Cheng
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2014-11-06

3.  Cross-Linked Fluorescent Supramolecular Nanoparticles as Finite Tattoo Pigments with Controllable Intradermal Retention Times.

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Journal:  ACS Nano       Date:  2016-12-20       Impact factor: 15.881

4.  Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting.

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5.  The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides.

Authors:  Rujing Zhang; Nan Zheng; Ziyuan Song; Lichen Yin; Jianjun Cheng
Journal:  Biomaterials       Date:  2014-01-15       Impact factor: 12.479

6.  Nano-Sized Sunflower Polycations As Effective Gene Transfer Vehicles.

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Journal:  Small       Date:  2016-04-07       Impact factor: 13.281

7.  Porous silicon-graphene oxide core-shell nanoparticles for targeted delivery of siRNA to the injured brain.

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8.  Site-Specific Drug-Releasing Polypeptide Nanocarriers Based on Dual-pH Response for Enhanced Therapeutic Efficacy against Drug-Resistant Tumors.

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9.  Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy.

Authors:  Srijayaprakash B Uppada; Terrianne Erickson; Luke Wojdyla; David N Moravec; Ziyuan Song; Jianjun Cheng; Neelu Puri
Journal:  Int J Nanomedicine       Date:  2013-12-17

10.  Development of Polypeptide-based Nanoparticles for Non-viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL.

Authors:  Fatih M Uckun; Lloyd G Mitchell; Sanjive Qazi; Yang Liu; Nan Zheng; Dorothea E Myers; Ziyuan Song; Hong Ma; Jianjun Cheng
Journal:  EBioMedicine       Date:  2015-04-30       Impact factor: 8.143
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