Literature DB >> 23413107

Thermal tissue damage model analyzed for different whole-body SAR and scan durations for standard MR body coils.

Manuel Murbach1, Esra Neufeld, Myles Capstick, Wolfgang Kainz, David O Brunner, Theodoros Samaras, Klaas P Pruessmann, Niels Kuster.   

Abstract

PURPOSE: This article investigates the safety of radiofrequency induced local thermal hotspots within a 1.5T body coil by assessing the transient local peak temperatures as a function of exposure level and local thermoregulation in four anatomical human models in different Z-positions.
METHODS: To quantize the effective thermal stress of the tissues, the thermal dose model cumulative equivalent minutes at 43°C was employed, allowing the prediction of thermal tissue damage risk and the identification of potentially hazardous MR scan-scenarios. The numerical results were validated by B1 (+) - and skin temperature measurements.
RESULTS: At continuous 4 W/kg whole-body exposure, peak tissue temperatures of up to 42.8°C were computed for the thermoregulated model (60°C in nonregulated case). When applying cumulative equivalent minutes at 43°C damage thresholds of 15 min (muscle, skin, fat, and bone) and 2 min (other), possible tissue damage cannot be excluded after 25 min for the thermoregulated model (4 min in nonregulated).
CONCLUSION: The results are found to be consistent with the history of safe use in MR scanning, but not with current safety guidelines. For future safety concepts, we suggest to use thermal dose models instead of temperatures or SAR. Special safety concerns for patients with impaired thermoregulation (e.g., the elderly, diabetics) should be addressed.
Copyright © 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  CEM43; SAR; local field enhancement; safety; thermal dose

Mesh:

Year:  2013        PMID: 23413107     DOI: 10.1002/mrm.24671

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN: 0740-3194            Impact factor:   4.668


  19 in total

1.  Advances in Computational Human Phantoms and Their Applications in Biomedical Engineering - A Topical Review.

Authors:  Wolfgang Kainz; Esra Neufeld; Wesley E Bolch; Christian G Graff; Chan Hyeong Kim; Niels Kuster; Bryn Lloyd; Tina Morrison; Paul Segars; Yeon Soo Yeom; Maria Zankl; X George Xu; Benjamin M W Tsui
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2019-01

2.  Parallel transmission RF pulse design with strict temperature constraints.

Authors:  Cem M Deniz; Giuseppe Carluccio; Christopher Collins
Journal:  NMR Biomed       Date:  2017-02-10       Impact factor: 4.044

3.  Pregnant women models analyzed for RF exposure and temperature increase in 3T RF shimmed birdcages.

Authors:  Manuel Murbach; Esra Neufeld; Theodoros Samaras; Juan Córcoles; Fraser J Robb; Wolfgang Kainz; Niels Kuster
Journal:  Magn Reson Med       Date:  2016-05-13       Impact factor: 4.668

4.  Radiofrequency heating studies on anesthetized swine using fractionated dipole antennas at 10.5 T.

Authors:  Yiğitcan Eryaman; Russell L Lagore; M Arcan Ertürk; Lynn Utecht; Patrick Zhang; Angel Torrado-Carvajal; Esra Abaci Türk; Lance DelaBarre; Gregory J Metzger; Gregor Adriany; Kâmil Uğurbil; J Thomas Vaughan
Journal:  Magn Reson Med       Date:  2017-03-31       Impact factor: 4.668

5.  Predicting long-term temperature increase for time-dependent SAR levels with a single short-term temperature response.

Authors:  Giuseppe Carluccio; Mary Bruno; Christopher M Collins
Journal:  Magn Reson Med       Date:  2015-06-22       Impact factor: 4.668

6.  Effects of Anatomical Differences on Electromagnetic Fields, SAR, and Temperature Change.

Authors:  Leeor Alon; Cem Murat Deniz; Giuseppe Carluccio; Ryan Brown; Daniel K Sodickson; Christopher M Collins
Journal:  Concepts Magn Reson Part B Magn Reson Eng       Date:  2015-12-15       Impact factor: 1.176

7.  Fetal MRI: A Technical Update with Educational Aspirations.

Authors:  Ali Gholipour; Judith A Estroff; Carol E Barnewolt; Richard L Robertson; P Ellen Grant; Borjan Gagoski; Simon K Warfield; Onur Afacan; Susan A Connolly; Jeffrey J Neil; Adam Wolfberg; Robert V Mulkern
Journal:  Concepts Magn Reson Part A Bridg Educ Res       Date:  2014-11       Impact factor: 0.481

8.  Functionalized anatomical models for EM-neuron Interaction modeling.

Authors:  Esra Neufeld; Antonino Mario Cassará; Hazael Montanaro; Niels Kuster; Wolfgang Kainz
Journal:  Phys Med Biol       Date:  2016-05-25       Impact factor: 3.609

9.  Investigation of assumptions underlying current safety guidelines on EM-induced nerve stimulation.

Authors:  Esra Neufeld; Ioannis Vogiatzis Oikonomidis; Maria Ida Iacono; Leonardo M Angelone; Wolfgang Kainz; Niels Kuster
Journal:  Phys Med Biol       Date:  2016-05-25       Impact factor: 3.609

Review 10.  [Test methods to determine magnetic resonance (MR) safety and MR image compatibility of implants/devices].

Authors:  Gregor Schaefers
Journal:  Radiologe       Date:  2019-10       Impact factor: 0.635

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