Literature DB >> 23412848

Correlation analysis on central lymph node metastasis in 276 patients with cN0 papillary thyroid carcinoma.

Wendong Wang1, Jialei Gu, Jinbiao Shang, Kejing Wang.   

Abstract

OBJECTIVE: To explore the relationship between sex, age, capsule invasion, tumor size, tumor location, number and central lymph node metastasis.
METHODS: Correlation analysis was conducted on clinical data of 276 patients with cN0 papillary thyroid carcinoma who underwent central lymph node dissection.
RESULTS: There was significant difference between patients less than 45 years old and greater than or equal 45 years old (P<0.05), between patients with capsule invasion and without capsule invasion (P<0.05); there were significant differences in the central lymph node metastasis rate between group with Φ≤0.5cm as well as Φ>2cm and the other three groups (P<0.05), and there was significant difference between upper pole group and middle/lower pole group (P<0.05) while no significant difference was found between middle pole and lower pole (P>0.05); there was also no significant difference in the central lymph node metastasis rate between groups with 1 tumor and greater as well as equal 2 (P>0.05).
CONCLUSION: We considered the tumor located in middle and lower pole, Φ>0.5cm of tumor size, less than 45 years old and the present of capsule invasion were high risk factors of central lymph node metastasis, so we strongly recommend performing central lymph node dissection in synchronization.

Entities:  

Keywords:  Hyroid tumors; lymph node metastasis; neck dissection; papillary carcinoma

Mesh:

Year:  2013        PMID: 23412848      PMCID: PMC3563193     

Source DB:  PubMed          Journal:  Int J Clin Exp Pathol        ISSN: 1936-2625


  17 in total

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6.  Papillary thyroid microcarcinoma: a study of 900 cases observed in a 60-year period.

Authors:  Ian D Hay; Maeve E Hutchinson; Tomas Gonzalez-Losada; Bryan McIver; Megan E Reinalda; Clive S Grant; Geoffrey B Thompson; Thomas J Sebo; John R Goellner
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7.  Extrathyroidal extension is not all equal: Implications of macroscopic versus microscopic extent in papillary thyroid carcinoma.

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8.  Central lymph node metastases in unilateral papillary thyroid microcarcinoma.

Authors:  Y C Lim; E C Choi; Y-H Yoon; E-H Kim; B S Koo
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  17 in total

1.  Prediction of central lymph node metastasis in 392 patients with cervical lymph node-negative papillary thyroid carcinoma in Eastern China.

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2.  Risk factors for central neck lymph node metastases in follicular variant vs. classic papillary thyroid carcinoma.

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4.  Risk Factors for Central Neck Lymph Node Metastases in Micro- Versus Macro- Clinically Node Negative Papillary Thyroid Carcinoma.

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Journal:  World J Surg       Date:  2018-03       Impact factor: 3.352

5.  MRI and ultrasonography detection of cervical lymph node metastases in differentiated thyroid carcinoma before reoperation.

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6.  Risk factors for central lymph node metastasis of patients with papillary thyroid microcarcinoma: a meta-analysis.

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Review 7.  Risk Factors for Central Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.

Authors:  Wei Sun; Xiabin Lan; Hao Zhang; Wenwu Dong; Zhihong Wang; Liang He; Ting Zhang; Siming Liu
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8.  Risk factors of central lymph node metastasis in cN0 papillary thyroid carcinoma: a study of 529 patients.

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9.  Total thyroidectomy without prophylactic central neck dissection in clinically node-negative papillary thyroid cancer: is it an adequate treatment?

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10.  A Study on Central Lymph Node Metastasis in 543 cN0 Papillary Thyroid Carcinoma Patients.

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