| Literature DB >> 23408144 |
Abstract
Aromatase Inhibitors are anti-estrogen agents that have proven efficacy for adjuvant therapy of estrogen receptor positive breast cancer primarily in post menopausal women with estrogen receptor positive breast cancer but increase the risk of cancer therapy induced bone loss (CTIBL). Recent studies have shown the potential benefit of bisphosphonate therapy to play a dual role in the management of breast cancer. These studies provide evidence that bisphosphonate therapy in conjunction with aromatase inhibitors (AI), not only decreases the risk of osteoporosis but, in addition, may improve survival from breast cancer.Entities:
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Year: 2013 PMID: 23408144 DOI: 10.1007/s11914-013-0134-7
Source DB: PubMed Journal: Curr Osteoporos Rep ISSN: 1544-1873 Impact factor: 5.096