Literature DB >> 23406208

DNA methylation biomarkers of stool and blood for early detection of colon cancer.

Liu Hong1, Nita Ahuja.   

Abstract

Detection of colorectal cancer at an early stage may significantly decrease mortality from the disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in the general public is rather low. Availability of a blood- or stool-based test of DNA methylation markers is expected to improve the screening compliance for colon cancer in the general population. The goal of this review is to describe the recent advances in DNA methylation markers of stool and blood for early detection of colon cancer, and envisage future developments toward their clinical availability. More investigations should be performed to promote both basic and clinical research of DNA methylation markers in patients with colon cancer.

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Year:  2013        PMID： 23406208     DOI： 10.1089/gtmb.2012.0478

Source DB:  PubMed          Journal:  Genet Test Mol Biomarkers        ISSN： 1945-0257


  8 in total

1.  Case-control study of candidate gene methylation and adenomatous polyp formation.

Authors:  M Alexander; J B Burch; S E Steck; C-F Chen; T G Hurley; P Cavicchia; N Shivappa; J Guess; H Zhang; S D Youngstedt; K E Creek; S Lloyd; K Jones; J R Hébert
Journal:  Int J Colorectal Dis       Date:  2016-10-22       Impact factor: 2.571

2.  Validation of methylation biomarkers that distinguish normal colon mucosa of cancer patients from normal colon mucosa of patients without cancer.

Authors:  Matteo Cesaroni; Jasmine Powell; Carmen Sapienza
Journal:  Cancer Prev Res (Phila)       Date:  2014-05-07

Review 3.  Epigenetic Determinants of Cancer.

Authors:  Stephen B Baylin; Peter A Jones
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-09-01       Impact factor: 10.005

Review 4.  DNA Methyltransferase Activity Assays: Advances and Challenges.

Authors:  Wan Jun Poh; Cayden Pang Pee Wee; Zhiqiang Gao
Journal:  Theranostics       Date:  2016-01-06       Impact factor: 11.556

5.  Bioinformatics analysis of methylation in cervical adenocarcinoma in Xinjiang, China.

Authors:  Min Yuan; Jianlin Yuan; Lipa Mei; Guzhalinuer Abulizi
Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.817

6.  Relation between expression of hMLH1 and p53 mRNA genes, in the feces of patients with colorectal carcinoma. Cross-sectional study.

Authors:  Ryanto Karobuana Sitepu; Rosdiana Natzir; Mochammad Hatta; Reno Rudiman; Ibrahim Labeda; Ronald E Lusikooy; Agussalim Bukhari; Upik A Miskad; Burhanuddin Bahar
Journal:  Ann Med Surg (Lond)       Date:  2022-01-06

7.  Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

Authors:  Zheng Feng; Cary J G Oberije; Alouisa J P van de Wetering; Alexander Koch; Kim A D Wouters; Nathalie Vaes; Ad A M Masclee; Beatriz Carvalho; Gerrit A Meijer; Maurice P Zeegers; James G Herman; Veerle Melotte; Manon van Engeland; Kim M Smits
Journal:  Clin Transl Gastroenterol       Date:  2022-06-01       Impact factor: 4.396

Review 8.  Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis.

Authors:  Zhifu Sun; Julie Cunningham; Susan Slager; Jean-Pierre Kocher
Journal:  Epigenomics       Date:  2015-09-14       Impact factor: 4.778
  8 in total

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