Literature DB >> 23403318

HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.

Haidar Akl, Ilse Vandecaetsbeek, Giovanni Monaco, Alexandre Kauskot, Tomas Luyten, Kirsten Welkenhuyzen, Marc Hoylaerts, Humbert De Smedt, Jan B Parys, Geert Bultynck.   

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Year:  2013        PMID: 23403318      PMCID: PMC3660005          DOI: 10.3324/haematol.2012.080598

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  12 in total

1.  Bcl-xL-inhibitory BH3 mimetics (ABT-737 or ABT-263) and the modulation of cytosolic calcium flux and platelet function.

Authors:  Simone M Schoenwaelder; Shaun P Jackson
Journal:  Blood       Date:  2012-02-02       Impact factor: 22.113

2.  Programmed anuclear cell death delimits platelet life span.

Authors:  Kylie D Mason; Marina R Carpinelli; Jamie I Fletcher; Janelle E Collinge; Adrienne A Hilton; Sarah Ellis; Priscilla N Kelly; Paul G Ekert; Donald Metcalf; Andrew W Roberts; David C S Huang; Benjamin T Kile
Journal:  Cell       Date:  2007-03-23       Impact factor: 41.582

3.  Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

Authors:  Victoria Del Gaizo Moore; Jennifer R Brown; Michael Certo; Tara M Love; Carl D Novina; Anthony Letai
Journal:  J Clin Invest       Date:  2007-01       Impact factor: 14.808

4.  Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores.

Authors:  Matthew T Harper; Alastair W Poole
Journal:  Blood       Date:  2012-05-03       Impact factor: 22.113

5.  Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.

Authors:  David Hermanson; Sadiya N Addo; Anna A Bajer; Jonathan S Marchant; Sonia Goutam Kumar Das; Balasubramanian Srinivasan; Fawaz Al-Mousa; Francesco Michelangeli; David D Thomas; Tucker W Lebien; Chengguo Xing
Journal:  Mol Pharmacol       Date:  2009-06-26       Impact factor: 4.436

6.  BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.

Authors:  Meike Vogler; Hassan A Hamali; Xiao-Ming Sun; Edward T W Bampton; David Dinsdale; Roger T Snowden; Martin J S Dyer; Alison H Goodall; Gerald M Cohen
Journal:  Blood       Date:  2011-05-11       Impact factor: 22.113

7.  An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Authors:  Tilman Oltersdorf; Steven W Elmore; Alexander R Shoemaker; Robert C Armstrong; David J Augeri; Barbara A Belli; Milan Bruncko; Thomas L Deckwerth; Jurgen Dinges; Philip J Hajduk; Mary K Joseph; Shinichi Kitada; Stanley J Korsmeyer; Aaron R Kunzer; Anthony Letai; Chi Li; Michael J Mitten; David G Nettesheim; ShiChung Ng; Paul M Nimmer; Jacqueline M O'Connor; Anatol Oleksijew; Andrew M Petros; John C Reed; Wang Shen; Stephen K Tahir; Craig B Thompson; Kevin J Tomaselli; Baole Wang; Michael D Wendt; Haichao Zhang; Stephen W Fesik; Saul H Rosenberg
Journal:  Nature       Date:  2005-05-15       Impact factor: 49.962

8.  Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.

Authors:  Jean-Paul Decuypere; Kirsten Welkenhuyzen; Tomas Luyten; Raf Ponsaerts; Michael Dewaele; Jordi Molgó; Patrizia Agostinis; Ludwig Missiaen; Humbert De Smedt; Jan B Parys; Geert Bultynck
Journal:  Autophagy       Date:  2011-12       Impact factor: 16.016

9.  Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.

Authors:  Leonard Dode; Jens Peter Andersen; Natalie Leslie; Jittima Dhitavat; Bente Vilsen; Alain Hovnanian
Journal:  J Biol Chem       Date:  2003-09-15       Impact factor: 5.157

10.  Physical properties of two types of calcium stores and SERCAs in human platelets.

Authors:  Alfonsas Juska; Isaac Jardin; Juan A Rosado
Journal:  Mol Cell Biochem       Date:  2007-12-16       Impact factor: 3.396

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  8 in total

Review 1.  Bcl-2 proteins and calcium signaling: complexity beneath the surface.

Authors:  T Vervliet; J B Parys; G Bultynck
Journal:  Oncogene       Date:  2016-03-14       Impact factor: 9.867

Review 2.  BH4 domain of Bcl-2 as a novel target for cancer therapy.

Authors:  Zhiqing Liu; Christopher Wild; Ye Ding; Na Ye; Haiying Chen; Eric A Wold; Jia Zhou
Journal:  Drug Discov Today       Date:  2015-11-26       Impact factor: 7.851

3.  BH3 mimetic-elicited Ca2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca2+-like peptides.

Authors:  Pawel E Ferdek; Monika A Jakubowska; Polina Nicolaou; Julia V Gerasimenko; Oleg V Gerasimenko; Ole H Petersen
Journal:  Cell Death Dis       Date:  2017-03-02       Impact factor: 8.469

Review 4.  Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.

Authors:  Martijn Kerkhofs; Mart Bittremieux; Giampaolo Morciano; Carlotta Giorgi; Paolo Pinton; Jan B Parys; Geert Bultynck
Journal:  Cell Death Dis       Date:  2018-02-28       Impact factor: 8.469

5.  On BH3 Mimetics and Ca2+ Signaling.

Authors:  Pawel E Ferdek; Monika A Jakubowska
Journal:  Drug Dev Res       Date:  2017-08-13       Impact factor: 4.360

6.  ABT-199 (Venetoclax), a BH3-mimetic Bcl-2 inhibitor, does not cause Ca2+ -signalling dysregulation or toxicity in pancreatic acinar cells.

Authors:  Monika A Jakubowska; Martijn Kerkhofs; Claudio Martines; Dimitar G Efremov; Julia V Gerasimenko; Oleg V Gerasimenko; Ole H Petersen; Geert Bultynck; Tim Vervliet; Pawel E Ferdek
Journal:  Br J Pharmacol       Date:  2018-11-08       Impact factor: 8.739

Review 7.  The multiple mechanisms of MCL1 in the regulation of cell fate.

Authors:  Hayley Widden; William J Placzek
Journal:  Commun Biol       Date:  2021-09-02

8.  TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.

Authors:  Fausto A Varela; Victoria L Foust; Thomas E Hyland; Kimberley E Sala-Hamrick; Jacob R Mackinder; Carly E Martin; Andrew S Murray; Sokol V Todi; Karin List
Journal:  Sci Rep       Date:  2020-08-17       Impact factor: 4.996

  8 in total

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