Literature DB >> 22308285

Bcl-xL-inhibitory BH3 mimetics (ABT-737 or ABT-263) and the modulation of cytosolic calcium flux and platelet function.

Simone M Schoenwaelder, Shaun P Jackson.   

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Year:  2012        PMID： 22308285     DOI： 10.1182/blood-2011-10-387399

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  14 in total

1.  HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.

Authors:  Haidar Akl; Ilse Vandecaetsbeek; Giovanni Monaco; Alexandre Kauskot; Tomas Luyten; Kirsten Welkenhuyzen; Marc Hoylaerts; Humbert De Smedt; Jan B Parys; Geert Bultynck
Journal:  Haematologica       Date:  2013-02-12       Impact factor: 9.941

2.  Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets.

Authors:  Hyo-Jung Choo; Andaleb Kholmukhamedov; ChengZing Zhou; Shawn Jobe
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-06-29       Impact factor: 8.311

Review 3.  Bcl-2 proteins and calcium signaling: complexity beneath the surface.

Authors:  T Vervliet; J B Parys; G Bultynck
Journal:  Oncogene       Date:  2016-03-14       Impact factor: 9.867

Review 4.  Targeting malignant mitochondria with therapeutic peptides.

Authors:  Jonathan E Constance; Carol S Lim
Journal:  Ther Deliv       Date:  2012-08

5.  Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets.

Authors:  Swapan K Dasgupta; Anhquyen Le; Sandra B Haudek; Mark L Entman; Rolando E Rumbaut; Perumal Thiagarajan
Journal:  PLoS One       Date:  2013-12-16       Impact factor: 3.240

6.  Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines.

Authors:  Hosadurga K Keerthy; Manoj Garg; Chakrabhavi D Mohan; Vikas Madan; Deepika Kanojia; Rangappa Shobith; Shivananju Nanjundaswamy; Daniel J Mason; Andreas Bender; Kanchugarakoppal S Rangappa; H Phillip Koeffler
Journal:  PLoS One       Date:  2014-09-30       Impact factor: 3.240

7.  Antagonism of Bcl-XL is necessary for synergy between carboplatin and BH3 mimetics in ovarian cancer cells.

Authors:  Mohammed Najim Abed; Marwan Ibrahim Abdullah; Alan Richardson
Journal:  J Ovarian Res       Date:  2016-04-14       Impact factor: 4.234

8.  A phase 1 study of the BCL2-targeted deoxyribonucleic acid inhibitor (DNAi) PNT2258 in patients with advanced solid tumors.

Authors:  Anthony W Tolcher; Wendi V Rodrigueza; Drew W Rasco; Amita Patnaik; Kyriakos P Papadopoulos; Alex Amaya; Timothy D Moore; Shari K Gaylor; Charles L Bisgaier; Mina P Sooch; Michael J Woolliscroft; Richard A Messmann
Journal:  Cancer Chemother Pharmacol       Date:  2013-12-03       Impact factor: 3.333

9.  The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria.

Authors:  A Fouqué; E Lepvrier; L Debure; Y Gouriou; M Malleter; V Delcroix; M Ovize; T Ducret; C Li; M Hammadi; P Vacher; P Legembre
Journal:  Cell Death Differ       Date:  2016-07-01       Impact factor: 15.828

10.  Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo.

Authors:  Liang Zhou; Yu Zhang; Deepak Sampath; Joel Leverson; Yun Dai; Maciej Kmieciak; Matthew Nguyen; Robert Z Orlowski; Steven Grant
Journal:  Br J Cancer       Date:  2017-12-14       Impact factor: 7.640
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